(R)-ADX-47273 |
| Katalog-Nr.GC34985 |
(R)-ADX-47273 ist ein potenter mGluR5 positiver allosterischer Modulator mit einem EC50 von 168 nM zur Potenzierung .
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 851881-59-9
Sample solution is provided at 25 µL, 10mM.
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(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator, with an EC50 of 168 nM for potentiation . mGluR5|168 nM (EC50)
(R)-ADX-47273 (ADX-47273 (5)) is a potent mGluR5 positive allosteric modulator with an EC50 for potentiation of 168 nM and a 9-fold shift of the glutamate response curve at 1 μM[1].
[1]. Engers DW, et al. Synthesis, SAR and unanticipated pharmacological profiles of analogues of the mGluR5 ago-potentiator ADX-47273. ChemMedChem. 2009 Apr;4(4):505-11.
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