ALK-IN-5 |
| Katalog-Nr.GC35289 |
ALK-IN-5 ist ein potenter, selektiver und in das Gehirn eindringender Inhibitor der anaplastischen Lymphomkinase (ALK) mit einem IC50 von 2,9 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2351929-66-1
Sample solution is provided at 25 µL, 10mM.
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ALK-IN-5 is a potent, selective, and brain-penetrant inhibitor of anaplastic lymphoma kinase (ALK), with an IC50 of 2.9 nM[1]. IC50: 2.9 nM (ALK)[1]
ALK-IN-5 potently inhibits ALK with cellular IC50 of 27 nM[1].
[1]. Fushimi M, et al. Discovery of Potent, Selective, and Brain-Penetrant 1 H-Pyrazol-5-yl-1 H-pyrrolo[2,3- b]pyridines as Anaplastic Lymphoma Kinase (ALK) Inhibitors. J Med Chem. 2019 May 23;62(10):4915-4935.
Average Rating: 5 (Based on Reviews and 7 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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