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p5 Ligand for Dnak and DnaJ

Katalog-Nr.GC36834

Der p5-Ligand fÜr Dnak und DnaJ ist ein Nonapeptid, das der Hauptbindungsstelle fÜr den 23-Rest-Teil der PrÄsequenz der mitochondrialen Aspartat-Aminotransferase entspricht.

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p5 Ligand for Dnak and DnaJ Chemische Struktur

Cas No.: 209518-24-1

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Sample solution is provided at 25 µL, 10mM.

Description of p5 Ligand for Dnak and DnaJ

p5 Ligand for Dnak and DnaJ is a nonapeptide, which corresponds to the main binding site for the 23-residue part of the presequence of mitochondrial aspartate aminotransferase. p5 Ligand for Dnak and DnaJ is a high-affinity ligand for DnaK and DnaJ[1].

[1]. Swain JF, et al. Hsp70 chaperone ligands control domain association via an allosteric mechanism mediated by the interdomain linker. Mol Cell. 2007 Apr 13;26(1):27-39.

Chemical Properties of p5 Ligand for Dnak and DnaJ

Cas No. 209518-24-1 SDF
Formula C44H81N15O11S M.Wt 1028.27
Löslichkeit Soluble in DMSO Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of p5 Ligand for Dnak and DnaJ

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 972.5 μL 4.8625 mL 9.7251 mL
5 mM 194.5 μL 972.5 μL 1.945 mL
10 mM 97.3 μL 486.3 μL 972.5 μL
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In vivo Formulation Calculator (Clear solution) of p5 Ligand for Dnak and DnaJ

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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