β-Boswellic acid |
| Katalog-Nr.GC38000 |
- Boswelliasäure wird aus dem Gummiharz von Boswellia serrate isoliert . β-Boswelliasäure hemmt die Synthese von DNA, RNA und Protein in menschlichen Leukämie-HL-60-Zellen.
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Cas No.: 631-69-6
Sample solution is provided at 25 µL, 10mM.
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β-Boswellic acid is isolated from the gum resin of Boswellia serrate.β-Boswellic acid is a nonreducing-type inhibitor of the 5-lipoxygenase (5-LO) product formation either interacting directly with the 5-LO or blocking its translocation[1]. β-Boswellic acid inhibits the synthesis of DNA, RNA and protein in human leukemia HL-60 cells[2].
[1]. Safayhi H, et al. Boswellic acids: novel, specific, nonredox inhibitors of 5-lipoxygenase. J Pharmacol Exp Ther. 1992 Jun;261(3):1143-6. [2]. Shao Y, et al. Inhibitory activity of boswellic acids from Boswellia serrata against human leukemia HL-60 cellsin culture. Planta Med. 1998 May;64(4):328-31
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