PTD-p65-P1 Peptide TFA |
| Katalog-Nr.GC38520 |
PTD-p65-P1-Peptid TFA ist ein potenter, selektiver Inhibitor des nuklearen Transkriptionsfaktors NF-κB und leitet sich von der p65-Untereinheit der NF-κB-AminosÄurereste 271-282 ab, die selektiv die NF-κB-Aktivierung, die durch verschiedene EntzÜndungsstimulationen induziert wird, herunter hemmt -regulieren die NF-κB-vermittelte Genexpression und regulieren die Apoptose hoch.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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PTD-p65-P1 Peptide TFA is a nuclear transcription factor NF-kappaB inhibitor, composed of a membrane-translocating peptide sequence generated from antennapedia (PTD) conjugated with p65-P1, which selectively inhibits activation induced by various inflammatory stimuli[1].
[1]. Takada Y, et al. Identification of a p65 peptide that selectively inhibits NF-kappa B activation induced by various inflammatory stimuli and its role in down-regulation of NF-kappaB-mediated gene expression and up-regulation of apoptosis. J Biol Chem. 2004 Apr 9;279(15):15096-104.
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