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α-Linolenic Acid-d5 MaxSpec• Standard (Synonyms: ALA-d5, C18:3 (9Z,12Z,15Z)-d5, C18:3 n-3-d5)

Katalog-Nr.GC45602

 

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α-Linolenic Acid-d5 MaxSpec• Standard Chemische Struktur

Cas No.: 145191-04-4

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100μg
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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

α-Linolenic acid-d5 (ALA-d5) is intended for use as an internal standard for the quantification of ALA by GC- or LC-MS. α-Linolenic acid is an essential ω-3 polyunsaturated fatty acid found in plants.1 In vivo, it is converted to the longer-chain fatty acids eicosapentaenoic , docosapentaenoic , and docosahexaenoic acid .2 It is also catabolized via fatty acid β-oxidation for energy or the synthesis of saturated and monounsaturated fatty acids, or stored in adipose tissue. Dietary consumption of ALA-containing foods is positively associated with a moderately lower risk of cardiovascular disease.1 ALA-d5 MaxSpec• standard is a quantitative grade standard of ALA-d5 that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This ALA-d5 MaxSpec• standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.

References
1. Pan, A., Chen, M., Chowdhury, R., et al. α-Linolenic acid and risk of cardiovascular disease: A systematic review and meta-analysis. Am. J. Clin. Nutr. 96(6), 1262-1273 (2012).
2. Burdge, G.C. Metabolism of α-linolenic acid in humans. Prostaglandins Leukot. Essent. Fatty Acids 75(3), 161-168 (2006).

Chemical Properties

Cas No. 145191-04-4 SDF
Überlieferungen ALA-d5, C18:3 (9Z,12Z,15Z)-d5, C18:3 n-3-d5
Canonical SMILES [2H]C([2H])([2H])C([2H])([2H])/C=C\C/C=C\C/C=C\CCCCCCCC(O)=O
Formula C18H25D5O2 M.Wt 283.5
Löslichkeit Soluble in DMSO Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 3.5273 mL 17.6367 mL 35.2734 mL
5 mM 0.7055 mL 3.5273 mL 7.0547 mL
10 mM 0.3527 mL 1.7637 mL 3.5273 mL
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Gewicht
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Konzentration
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Inhalt
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**Bei der Herstellung von Stammlösungen ist immer das chargenspezifische Molekulargewicht von

Berechnen

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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