Hexanoyl Glycine (Synonyms: NSC 224460) |
| Katalog-Nr.GC40558 |
Hexanoyl glycine is an acylated amino acid that is used as a urinary biomarker for several indications.
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Cas No.: 24003-67-6
Sample solution is provided at 25 µL, 10mM.
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Hexanoyl glycine is an acylated amino acid that is used as a urinary biomarker for several indications. It is normally biosynthesized from hexanoyl-CoA and glycine by the mitochondrial enzyme glycine N-acyltransferase. Increased urinary excretion of hexanoyl glycine in humans is indicative of a deficiency in medium-chain acyl-CoA dehydrogenase. Increased urinary hexanoyl glycine can also be used as a biomarker for exposure to gamma radiation. Levels of hexanyl glycine can also be elevated during cancer, while they are decreased 20-fold in mice following treatment with the PPARα ligand Wy 14643.
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