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N-Demethylerythromycin A

Katalog-Nr.GC40852

N-Demethylerythromycin A is a metabolite of erythromycin.

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N-Demethylerythromycin A Chemische Struktur

Cas No.: 992-62-1

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500μg
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1mg
139,00 $
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5mg
308,00 $
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10mg
540,00 $
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Sample solution is provided at 25 µL, 10mM.

Description of N-Demethylerythromycin A

N-Demethylerythromycin A is a metabolite of erythromycin . It is also a fungal metabolite that has been found in S. erythreus and a potential impurity in commercial preparations of erythromycin.

Chemical Properties of N-Demethylerythromycin A

Cas No. 992-62-1 SDF
Canonical SMILES C[C@@H]([C@@H]([C@H](C(O[C@@H]1CC)=O)C)O[C@@]2([H])C[C@](OC)(C)[C@@H](O)[C@H](C)O2)[C@H]([C@@](O)(C)C[C@H](C([C@@H]([C@@H](O)[C@]1(C)O)C)=O)C)O[C@@](O[C@H](C)C[C@@H]3[NH]C)([H])[C@@H]3O
Formula C36H65NO13 M.Wt 719.9
Löslichkeit Chloroform: soluble,Methanol: soluble Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of N-Demethylerythromycin A

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 1.3891 mL 6.9454 mL 13.8908 mL
5 mM 0.2778 mL 1.3891 mL 2.7782 mL
10 mM 0.1389 mL 0.6945 mL 1.3891 mL
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In vivo Formulation Calculator (Clear solution) of N-Demethylerythromycin A

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 40 reference(s) in Google Scholar.)

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