(+)-Praeruptorin A |
| Katalog-Nr.GC40266 |
(+)-Praeruptorin A ist ein bioaktiver Hauptbestandteil von Peucedanum praeruptorum (auch bekannt als Bai-Hua Qian Hu).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 73069-27-9
Sample solution is provided at 25 µL, 10mM.
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(+)-Praeruptorin A is a coumarin derivative originally isolated from P. praeruptorum. It prevents LPS-induced increases in IL-1β and TNF-α in a concentration-dependent manner when used at concentrations ranging from 6.25 to 100 µM and IL-6 at concentrations ranging from 25 to 100 µM. It inhibits potassium chloride-induced contraction of isolated rabbit trachea by 50 and 100% when used at concentrations of 4.8 and 30 µM, respectively. Topical administration of (+)-praeruptorin A (0.3 µmol/cm2) reduces edema by 22% in a croton oil mouse model of inflammation.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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