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Prochlorperazine

Katalog-Nr.GC10788

Dopamine (D2) receptor antagonist

Products are for research use only. Not for human use. We do not sell to patients.

Prochlorperazine Chemische Struktur

Cas No.: 58-38-8

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50mg
38,00 $
Auf Lager
100mg
72,00 $
Auf Lager
250mg
171,00 $
Auf Lager
500mg
302,00 $
Auf Lager

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Sample solution is provided at 25 µL, 10mM.

Description of Prochlorperazine

Prochlorperazine (Compazine, Stemzine, Buccastem, Stemetil, Phenotil) is a dopamine (D2) receptor antagonist that belongs to the phenothiazine class of antipsychotic agents that are used for the antiemetic treatment of nausea and vertigo. It is also a highly potent typical antipsychotic, 10-20x more potent than chlorpromazine. It is also used to treat migraine headaches. Intravenous administration can be used to treat status migrainosus.

Chemical Properties of Prochlorperazine

Cas No. 58-38-8 SDF
Chemical Name 2-chloro-10-(3-(4-methylpiperazin-1-yl)propyl)-10H-phenothiazine
Canonical SMILES CN(CC1)CCN1CCCN2C3=CC=CC=C3SC4=C2C=C(Cl)C=C4
Formula C20H24ClN3S M.Wt 373.94
Löslichkeit ≥ 16.5mg/mL in DMSO Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Prochlorperazine

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.6742 mL 13.3711 mL 26.7423 mL
5 mM 534.8 μL 2.6742 mL 5.3485 mL
10 mM 267.4 μL 1.3371 mL 2.6742 mL
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Berechnen

In vivo Formulation Calculator (Clear solution) of Prochlorperazine

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Average Rating: 5 ★★★★★ (Based on Reviews and 1 reference(s) in Google Scholar.)

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