PSB-1584 |
| Katalog-Nr.GB40333 |
GPR84 is an orphan G protein-coupled receptor that is activated by medium-chain fatty acids and hydroxy fatty acids although these may not be its endogenous agonist.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 72255-76-6
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
GPR84 is an orphan G protein-coupled receptor that is activated by medium-chain fatty acids and hydroxy fatty acids although these may not be its endogenous agonist. It is highly expressed on immune cells and expression levels rise after exposure to inflammatory stimuli. Potent synthetic agonists enhance proinflammatory signaling and macrophage effector functions. PSB-1584 is a potent synthetic exogenous agonist at GPR84, EC50=5 nM which is selective against other free fatty acid receptors and is metabolically stable when incubated with human liver microsomes. An important new tool for studying the physiology of GPR84.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *