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(R)-3-Hydroxybutanoic acid sodium

Katalog-Nr.GC61759

(R)-3-HydroxybutansÄure-Natrium ((R)-3-HydroxybuttersÄure) ist ein Metabolit, der aus AcetessigsÄure umgewandelt wird, katalysiert durch 3-Hydroxybutyrat-Dehydrogenase.

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(R)-3-Hydroxybutanoic acid sodium Chemische Struktur

Cas No.: 13613-65-5

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Sample solution is provided at 25 µL, 10mM.

Description of (R)-3-Hydroxybutanoic acid sodium

(R)-3-Hydroxybutanoic acid sodium ((R)-3-Hydroxybutyric acid) is a metabolite converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase. (R)-3-Hydroxybutanoic acid sodium has applications as a nutrition source, and as a precursor for vitamins, antibiotics and pheromones[1][2].

(R)-3-Hydroxybutanoic acid sodium is a metabolite converted from acetoacetic acid. Enhanced hepatic fatty acid oxidation results in the increased production of acetoacetic acid which is in turn converted to (R)-3-Hydroxybutanoic acid sodium by a reaction catalyzed by 3-hydroxybutyrate dehydrogenase[1].

[1]. Ide T. Enzymatic-HPLC method to analyze D-3-hydroxybutyric acid in rat serum. Biosci Biotechnol Biochem. 2010;74(8):1578-82. [2]. Mateusz Biernacki, et al. Production of (R)-3-hydroxybutyric acid by Arxula adeninivorans. AMB Express. 2017 Dec;7(1):4.

Chemical Properties of (R)-3-Hydroxybutanoic acid sodium

Cas No. 13613-65-5 SDF
Canonical SMILES C[C@H](CC(O[Na])=O)O
Formula C4H7NaO3 M.Wt 126.09
Löslichkeit DMSO: 100 mg/mL (793.08 mM); Water: 100 mg/mL (793.08 mM) Storage Store at -20°C, filled inert atmosphere
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of (R)-3-Hydroxybutanoic acid sodium

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1 mg 5 mg 10 mg
1 mM 7.9308 mL 39.6542 mL 79.3084 mL
5 mM 1.5862 mL 7.9308 mL 15.8617 mL
10 mM 0.7931 mL 3.9654 mL 7.9308 mL
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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