(R)-FL118 (Synonyms: 10,11-(Methylenedioxy)-20(R)-camptothecin) |
| Katalog-Nr.GC65384 |
(R)-FL118 (10,11-(Methylendioxy)-20(R)-camptothecin) ist das R-Enantiomer von FL118. (R)-FL118 zeigt AntikrebsaktivitÄt.
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Cas No.: 151636-76-9
Sample solution is provided at 25 µL, 10mM.
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(R)-FL118 (10,11-(Methylenedioxy)-20(R)-camptothecin) is the R-enantiomer of FL118 . (R)-FL118 shows anticancer activity[1].
(R)-FL118 inhibits the growth of melanoma, breast, and prostate cancer cell lines, with IC50 values of 392.7, 32.53, 129.3, 138.7, and 92.51 ng/mL in B16, MCF-7, HS578T, DU145, and MPC3 cells, respectively[1].
[1]. Del Poeta M, et al. Comparison of in vitro activities of camptothecin and nitidine derivatives against fungal and cancer cells. Antimicrob Agents Chemother. 1999 Dec;43(12):2862-8.
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