(R,R)-CXCR2-IN-2 |
Katalog-Nr.GC62588 |
(R,R)-CXCR2-IN-2, Diastereoisomer von CXCR2-IN-2 (Verbindung 68), ist ein in das Gehirn eindringender CXCR2-Antagonist mit einem pIC50 von 9 und 6,8 im Tango-Assay und d im HWB-Gro-α-induzierten CD11b-Expressionsassay .
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1838123-22-0
Sample solution is provided at 25 µL, 10mM.
(R,R)-CXCR2-IN-2, diastereoisomer of CXCR2-IN-2 (compound 68), is a brain penetrant CXCR2 antagonist with a pIC50 of 9 and 6.8 in the Tango assay and d in the HWB Gro-α induced CD11b expression assay, respectively[1].
[1]. Lu H, et al. Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists. J Med Chem. 2018;61(6):2518-2532.
Average Rating: 5
(Based on Reviews and 20 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *