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(rac)-BAY1238097

Katalog-Nr.GC34446

(Rac)-BAY1238097 ist ein BET-Inhibitor mit einem IC50-Wert von 1,02 μM fÜr BRD4. Wird in der Krebsforschung verwendet.

Products are for research use only. Not for human use. We do not sell to patients.

(rac)-BAY1238097 Chemische Struktur

Cas No.: 1564268-19-4

Größe Preis Lagerbestand Menge
10mM (in 1mL DMSO)
194,00 $
Auf Lager
5mg
176,00 $
Auf Lager
10mg
269,00 $
Auf Lager
50mg
1.020,00 $
Auf Lager
100mg
1.808,00 $
Auf Lager

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

(rac)-BAY1238097 is a BET inhibitor, with an IC50 of 1.02 μM for BRD4. Used in cancer research[1]. IC50: 1.02 μM (BRD4)[1]

[1]. Stephan Siegel, et al. 2,3-benzodiazepines. WO2014026997A1.

Chemical Properties

Cas No. 1564268-19-4 SDF
Canonical SMILES CC1N(C(NC)=O)N=C(C2=CC=C(N3CCN(C)CC3)C=C2)C4=CC(OC)=C(OC)C=C4C1
Formula C25H33N5O3 M.Wt 451.56
Löslichkeit DMSO : 150 mg/mL (332.18 mM) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.2145 mL 11.0727 mL 22.1455 mL
5 mM 0.4429 mL 2.2145 mL 4.4291 mL
10 mM 0.2215 mL 1.1073 mL 2.2145 mL
  • Molaritätsrechner

  • Verdünnung-Rechner

Gewicht
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Konzentration
x
Inhalt
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MW*
 
 
 
**Bei der Herstellung von Stammlösungen ist immer das chargenspezifische Molekulargewicht von

Berechnen

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Review for (rac)-BAY1238097

Average Rating: 5 ★★★★★ (Based on Reviews and 9 reference(s) in Google Scholar.)

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