Atherosclerosis
Produkte für Atherosclerosis
- Bestell-Nr. Artikelname Informationen
- GC48283 α-Linolenic Acid-d14 An internal standard for the quantification of αLinolenic acid
- GC40467 (±)11-HETE (±)11-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid.
- GC41649 (±)13-HODE cholesteryl ester (±)13-HODE cholesteryl ester was originally extracted from atherosclerotic lesions and shown to be produced by Cu2+-catalyzed oxidation of LDL.
- GC41666 (±)9-HODE cholesteryl ester (±)9-HODE cholesteryl ester was originally extracted from atherosclerotic lesions and shown to be produced by Cu2+-catalyzed oxidation of LDL.
- GC49690 (3R,5R)-Rosuvastatin (calcium salt) A potential impurity found in bulk preparations of rosuvastatin
- GC46496 1-Stearoyl-2-Arachidonoyl-d8-sn-glycero-3-PC An internal standard for the quantification of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC
- GC41893 13(R)-HODE cholesteryl ester 13(R)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions.
- GC41895 13(S)-HODE cholesteryl ester 13(S)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions.
- GC41897 13(S)-HOTrE 13(S)-HOTrE is the 15-lipoxygenase (15-LO) product of linolenic acid.
- GC49671 2,3-Oxidosqualene An intermediate in the biosynthesis of sterols
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GC41614
24-dehydro Cholesterol
24-Dehydrocholesterin ist ein Molekül, das Cholesterin ähnelt.
- GC46243 24-dehydro Cholesterol-d6 An internal standard for the quantification of 24-dehydro cholesterol
- GC46528 25-hydroxy Cholesterol-d6 An internal standard for the quantification of 25hydroxy cholesterol
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GC42411
4-hydroxy Nonenal Alkyne
4-hydroxy Nonenal (4-HNE) is a major aldehyde produced during the lipid peroxidation of ω-6 polyunsaturated fatty acids, such as arachidonic acid and linoleic acid.
- GC40053 5α,6α-epoxy Cholestanol An oxysterol and a metabolite of cholesterol produced by oxidation
- GC45357 5-Chlorouracil
- GC49629 6β-hydroxy Prednisolone A metabolite of prednisolone
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GC40202
7α-hydroxy Cholesterol-d7
7α-hydroxy Cholesterol-d7 is intended for use as an internal standard for the quantification of 7α-hydroxy cholesterol by GC- or LC-MS.
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GC46241
7-keto Cholesterol-d7
7-keto Cholesterol is a bioactive sterol and a major oxysterol component of oxidized LDL
- GC42634 9(R)-HODE cholesteryl ester 9(R)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions.
- GC19460 9(S)-HODE 9(S)-HODE is produced by the lipoxygenation of linoleic acid in both plants and animals.
- GC42635 9(S)-HODE cholesteryl ester 9(S)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions.
- GC49784 AZD 2716 An sPLA2 inhibitor
- GC42890 Azelaoyl PAF Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which promote the differentiation of monocytes via the nuclear receptor PPARγ.
- GC46912 Beauveriolide III Beauveriolid III ist ein Inhibitor der Bildung von LipidtrÖpfchen in Maus-Makrophagen.
- GC42924 Beraprost (sodium salt) Beraprost is an analog of prostacyclin in which the unstable enol-ether has been replaced by a benzofuran ether function.
- GC42994 Butanoyl PAF Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which promote the differentiation of monocytes and activate polymorphonuclear leukocytes.
- GC43136 Campestanol Campestanol ist ein Phytosterin, das in pflanzlicher Nahrung vorkommt.
- GC43160 CAY10485 Acyl-coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis.
- GC41636 CAY10487 The early stage of atherosclerosis is characterized by the aggregation of foam cells, so called a fatty streak, in the inner arterial wall.
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GC40203
Cholesterol-d6
Cholesterol-d6 is intended for use as an internal standard for the quantification of cholesterol by GC- or LC-MS.
- GC47085 Cholesterol-d7 An internal standard for the quantification of cholesterol
- GC19433 Cholesteryl Heptadecanoate Cholesteryl heptadecanoate is a cholesterol ester (CE) formed by the condensation of cholesterol with heptadecanoic acid, a C-17 saturated fatty acid that does not occur in any natural animal or vegetable fat at high concentrations.
- GC43263 Cholesteryl Stearate Cholesteryl stearate is a cholesterol ester.
- GC45439 Docosahexaenoic Acid-d5 MaxSpec• Standard DocosahexaensÄure-d5 MaxSpec Standard (DHA-d5) ist die mit Deuterium markierte DocosahexaensÄure.
- GC52193 Eptifibatide Eptifibatid ist ein zyklisches Heptapeptid, das als kompetitiver Antagonist fÜr den aktivierten Thrombozyten-Glykoprotein-IIb/IIIa-Rezeptor mit Thrombozytenaggregationshemmung wirkt.
- GC33760 ETC-1002 (ESP-55016) ETC-1002 (ESP-55016) (ETC-1002) ist ein ATP-Citrat-Lyase (ACL)-Inhibitor.
- GC47397 Gemfibrozil-d6 An internal standard for the quantification of gemfibrozil
- GC48744 Gliclazide-d4 An internal standard for the quantification of gliclazide
- GC18788 Graphislactone A Graphislactone A is an antioxidant produced by Cephalosporium IFB-E001 and M.
- GC43803 HA-1077 (hydrochloride) Fasudil (HA-1077; AT877) dihydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μ ;M, 1.650 μM fÜr ROCK2 bzw. PKA, PKC, PKG. HA-1077 (Hydrochlorid) ist auch ein potenter Ca2+-Kanalantagonist und Vasodilatator.
- GC45469 Hexacosanoic Acid-d4
- GC49496 Homocitrulline-d3 An internal standard for the quantification of homocitrulline
- GC43997 KDdiA-PC KDdiA-PC ist eine Art oxidiertes LDL (oxLDL) und ein Ligand fÜr den Makrophagen-Scavenger-Rezeptor CD36.
- GC44011 KOdiA-PC Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic.
- GC52497 Lactosylceramide (porcine RBC) A sphingolipid
- GC40142 Lactosylceramides (bovine buttermilk) Lactosylceramide (LacCer) is an endogenous bioactive sphingolipid.
- GC52281 Losartan Azide A potential impurity in commercial preparations of losartan
- GC44093 Lutein Lutein is a natural yellow carotenoid, which can be found in plants, egg yolks, and in the human retina.
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GC18241
Lysophosphatidylcholines
Lysophosphatidylcholines are produced by hydrolysis of the fatty acid of phosphatidylcholine at either the sn-1 or sn-2 position by phospholipase A2 (PLA2) or by lecithin-cholesterol acyltranferase (LCAT), which transfers the fatty acid to cholesterol.
- GC49486 Meglutol-d3 An internal standard for the quantification of meglutol
- GC44180 Methylcarbamyl PAF C-16 Methylcarbamyl PAF C-16 is a stable analog of PAF C-16 with a half-life greater than 100 minutes in platelet poor plasma due to its resistance to degradation by PAF-AH.
- GC40624 MMP-3 Inhibitor VIII Matrix metalloproteinases (MMPs) belong to a family of proteases that play a crucial role in tissue remodeling and repair by degrading extracellular matrix proteins to enable cell migration.
- GC18616 MMP-8 Inhibitor I MMP-8 Inhibitor I is a selective inhibitor of the neutrophil collagenase matrix metalloproteinase-8 (MMP-8) with an IC50 value of 4 nM.
- GC20172 N-Isopropylphthalimide
- GC44518 Osteocalcin (1-49) (human) (trifluoroacetate salt) Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone.
- GC44573 PAz-PC Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic.
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GC44616
PGPC
PGPC is an oxidized phospholipid that can be formed under conditions of oxidative stress.
- GC44633 Phosphatidylserines (bovine) Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina.
- GC18522 Phosphatidylserines (sodium salt) Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina.
- GC49340 Pitavastatin lactone-d4 An internal standard for the quantification of pitavastatin lactone
- GC44669 POV-PC Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic.
- GC49107 Rosuvastatin lactone The lactone form of rosuvastatin
- GC48060 Rosuvastatin-d6 (sodium salt) An internal standard for the quantification of rosuvastatin
- GC44910 Sodium Hydrogen Sulfide (hydrate) Hydrogen sulfide (H2S) is, like nitric oxide, an important gaseous mediator that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals.
- GC45057 TIQ-A TIQ-A ist ein potenter TNKS (Poly-ART, PARP)-Inhibitor mit einem IC50-Wert von 24 nM fÜr TNKS2.
- GC48206 Trimethylamine-d9 N-oxide An internal standard for the quantification of trimethylamine N-oxide