Vasodilation
Produkte für Vasodilation
- Bestell-Nr. Artikelname Informationen
-
GC45200
α-CGRP (rat) (trifluoroacetate salt)
Calcitonin Gene-Related Peptide-1 (rat), α-Calcitonin Gene-Related Peptide (rat), CGRP-1 (rat)
α-Calcitonin gene-related peptide (α-CGRP) is a neuropeptide with roles in vasodilation, cardiovascular regulation, and inflammation. -
GC45602
α-Linolenic Acid-d5 MaxSpec• Standard
ALA-d5, C18:3 (9Z,12Z,15Z)-d5, C18:3 n-3-d5
-
GC40105
βARK1 Inhibitor
βARK1-Inhibitor (Methyl-5-[2-(5-nitro-2-furyl)vinyl]-2-furoat) ist ein GRK2 (β-ARK1)-Inhibitor.
-
GC41661
(±)-4-hydroxy Propranolol β-D-Glucuronide
(±)-4-hydroxy Propranolol β-D-glucuronide is a metabolite of (±)-4-hydroxy propranolol, which is a metabolite of propranolol.
-
GC46304
(±)-Nebivolol-d4 (hydrochloride)
A neuropeptide with diverse biological activities
-
GC90022
(±)-Norepinephrine-d6 (hydrochloride)
Ein interner Standard zur Quantifizierung von Norepinephrin.
-
GC46312
(±)-Verapamil-d3 (hydrochloride)
(±)-Verapamil-d3 hydrochloride; CP-16533-1-d3 hydrochloride
A neuropeptide with diverse biological activities -
GC40386
(±)11(12)-EpETE
(±)11,12-EEQ, (±)11,12-Epoxyeicosatetraenoic Acid
Eicosapentaenoic acid is converted to epoxyeicosatetraenoic acids (EpETE) by several cytochrome P450 isoforms. -
GC91065
(±)13,14-EDT
Ein Metabolit von Adreninsäure.
-
GC40430
(±)14(15)-EET
(±)14,15-EET, (±)14,15-EpETrE
(±)14(15)-EET is biosynthesized in rat and rabbit liver microsomes by CYP450.
-
GC40835
(±)14(15)-EET methyl ester
(±)14,15EpETrE methyl ester
(±)14(15)-EET is biosynthesized in rat and rabbit liver microsomes by CYP450. -
GC41651
(±)14(15)-EET-SI
14,15-EpETrE-SI, 14(15)-EET-SI, 14(15)EETsulfonimide
Arachidonic acid is metabolized in the vascular endothelium to epoxytrienoic acids (EETs or EpETrEs) by cytochrome P450 enzymes. -
GC91067
(±)16,17-EDT
Ein Metabolit von Adreninsäure.
-
GC41288
(±)17(18)-EpETE-Ethanolamide
17,18-EEQ-EA, (±)17,18-EEQ-Ethanolamide, (±)17(18)-EpETE-EA, 17,18-epoxy-Eicosatetraenoic Acid Ethanolamide
(±)17(18)-EpETE-Ethanolamide is an ω-3 endocannabinoid epoxide. -
GC40436
(±)18-HETE
(±)18-Hydroxyeicosatetraenoic Acid
(±)18-HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonic acid. -
GC41655
(±)19(20)-EDP Ethanolamide
19,20-DHEA epoxide, 19,20-epoxy Docosapentaenoic Acid Ethanolamide, 19,20-EDP-EA, 19,20-EDP epoxide
(±)19(20)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 108 and 280 nM for CB1 and CB2, respectively). -
GC40437
(±)5(6)-DiHET lactone
(±)5,6DiHETrE lactone
5,6-DiHET lactone is a lactonized form of 5,6-EET and 5,6-DiHET. -
GC40438
(±)5(6)-EET
(±)5,6EpETrE
5(6)-EET is a fully racemic version of the enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes. -
GC40421
(±)8(9)-EE-14(Z)-E
(±)8,9-Epoxyeicosa-14(Z)-enoic Acid
(±)14(15)-EE-8(Z)-E is a potent vasodilator in bovine coronary arteries. -
GC41697
(Ala1)-PAR4 (1-6) amide (mouse) (trifluoroacetate salt)
AY-NH2, AYPGKF-NH2, H-Ala-Tyr-Pro-Gly-Lys-Phe-NH2, PAR4-AP, Proteinase-Activated Receptor 4 Activating Peptide
(Ala1)-PAR4 (1-6) amide (mouse) is a peptide agonist of proteinase-activated receptor 4 (PAR4) that induces aggregation of rat and human platelets in vitro (EC50s = 15 and 60 μM, respectively). -
GC18637
11β-Prostaglandin F2α
9α,11βPGF2α, 11βPGF2α, 11epi PGF2α
11β-Prostaglandin F2α (11β-PGF2α) is the primary plasma metabolite of PGD2 in vivo.
-
GC46425
13,14-dihydro-15-keto Prostaglandin E1-d4
13,14dh15k PGE1d4
A neuropeptide with diverse biological activities -
GC40425
14,15-EE-8(Z)-E
14,15Epoxyeicosa8(Z)enoic Acid
Epoxyeicosatrienoic acids (EETs), such as 11(12)-EET and 14(15)-EET, are cytochrome P450 metabolites of arachidonic acid that have been identified as endothelium-derived hyperpolarizing factors with vasodilator activity. -
GC46438
14S(15R)-EET
14S,15R-EpETrE
A cytochrome P450 metabolite of arachidonic acid -
GC91109
17β-Estradiol 3-O-Sulfate (sodium salt)
Ein inaktives Stoffwechselprodukt von 17β-Östradiol.
-
GC40457
19(R)-HETE
19(R)-Hydroxyeicosatetraenoic Acid
19-HETE is one of the major cytochrome P450 (CYP450) metabolites of arachidonic acid that is released from the kidney in response to angiotensin II. -
GC90840
2-Chloroadenosine-5'-O-diphosphate (sodium salt)
Eine Ableitung von ADP.
-
GC42160
2-furoyl-LIGRLO amide (trifluoroacetate salt)
2-furoyl-LIGRLO amide is a potent and selective agonist of the proteinase-activated receptor, PAR2 (pD2 = 7.0).
-
GC40503
2-HOBA
2-(Aminomethyl)phenol, 2-Hydroxybenzylamine, NSC 127870
2-HOBA (2-HOBA), ein selektiver DicarbonylfÄnger, ist ein Antioxidans und FÄnger von freien Radikalen und Isolevuglandinen (IsoLGs). -
GC41104
20-carboxy Arachidonic Acid
20carboxy AA, 20COOHAA
20-carboxy Arachidonic acid (20-COOH-AA) is the major metabolite of 20-HETE that is produced in renal tubular epithelial, endothelial, and microvascular smooth muscle cell cultures. -
GC42409
4-hydroxy Nebivolol (hydrochloride)
4-hydroxy Nebivolol is a major metabolite of nebivolol.
-
GC46708
5'-N-Ethylcarboxamidoadenosine (hydrate)
Adenosine 5'-ethylcarboxamide, NECA
A neuropeptide with diverse biological activities -
GC40336
5-cis Carbaprostacyclin
(5Z)6aCarbaprostaglandin I2
5-cis Carbaprostacyclin is a stable analog of PGI2 and an isomer of carbaprostacyclin. -
GC40586
6β-Prostaglandin I1
6βPGI1, 5,6βdihydro PGI2
6β-PGI1 is a stable PGI2 analog resistant to hydrolysis in aqueous solutions. -
GC18820
6-keto Prostaglandin E1
6keto PGE1
6-keto PGE1 is a metabolite isolated after the incubation of PGI2 with rabbit liver microsomes. -
GC49576
Abnormal Cannabidiol-d3
Abn-CBD-d3, o-CBD, ortho-Cannabidiol
Internal standard for the quantification of abnormal cannabidiol -
GC42739
Adrenomedullin (1-50) amide (rat) (trifluoroacetate salt)
Adrenomedullin (1-50) is a peptide hormone with RNA expressed in rat adrenal glands, lung, kidney, heart, and spleen, as well as in the duodenum and submandibular glands.
-
GC42740
Adrenomedullin (1-52) (human) (trifluoroacetate salt)
Adrenomedullin (1-52)-NH2
Adrenomedullin (1-52) is a peptide with diverse biological activities. -
GC40158
Adrenomedullin (11-50) (rat) (trifluoroacetate salt)
Adrenomedullin (11-50) is a truncated form of rat adrenomedullin.
-
GC42738
Adrenomedullin (13-52) (human) (trifluoroacetate salt)
Adrenomedullin (13-52) is a truncated form of adrenomedullin (1-52).
-
GC42746
AFP 07 (free acid)
Prostaglandin I2 is an unstable prostanoid which, through the 'I prostanoid' (IP) receptor, inhibits platelet aggregation and promotes vasodilatation in pulmonary vascular beds.
-
GC52023
Alfuzosin-d7
SL 77499-10-d7, Uroxatral-d7
An internal standard for the quantification of alfuzosin -
GC42778
Amauromine
Amauromine is a neutral antagonist of the cannabinoid (CB) receptor CB1 that is selective for CB1 (Ki = 178 nM; Kb = 66.6 nM) over CB2, with no activity at CB2 receptors at concentrations up to 10 μM.
-
GC49638
Ambrisentan-d3
An internal standard for the quantification of ambrisentan
-
GC46856
Angiotensin II (5-8) (human, rat, mouse) (trifluoroacetate salt)
Angiotensin (5-8)
An endogenous angiotensin II fragment
-
GC52427
Apelin-12 (human, mouse, rat, bovine) (acetate)
RPRLSHKGPMPF
An endogenous agonist of the APJ receptor -
GC49314
Arecaidine propargyl ester (hydrobromide)
APE
A muscarinic M2 agonist -
GC49057
Azelastine-13C-d3 (hydrochloride)
An internal standard for the quantification of azelastine
-
GC18313
BAR501 Impurity
BAR501 impurity is an impurity found in the preparation of BAR501 that acts as an agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1).
-
GC52145
Bradykinin (human, mouse, rat, bovine) (acetate)
Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH, BK, RPPGFSPFR-OH
-
GC49880
Bradykinin (trifluoroacetate salt)
An endogenous vasodilator
-
GC52424
Bradykinin Fragment (1-5) (trifluoroacetate salt)
Arg-Pro-Pro-Gly-Phe, BK1-5, RPPGF
A metabolite of bradykinin -
GC42970
Brain Natriuretic Peptide (1-32) (human) (trifluoroacetate salt)
BNP (1-32) (human)
Brain natriuretic peptide (BNP) (1-32) is an endogenous peptide that has cardiovascular functions and belongs to the family of natriuretic peptides, which includes atrial natriuretic peptide and C-type natriuretic peptide. -
GC91223
Brain Natriuretic Peptide-32 (rat) (acetate)
Ein natriuretisches Peptid
-
GC43328
C-Type Natriuretic Peptide-22 (human, porcine, rat) (trifluoroacetate salt)
CNP-22
C-Type natriuretic peptide-22 (CNP-22) is an endogenous peptide with diverse biological activities. -
GC47021
Caloxin 2A1 (trifluoroacetate salt)
VSNSNWPSFPSSGGG-NH2
A neuropeptide with diverse biological activities -
GC47045
Carvedilol-d5
An internal standard for the quantification of carvedilol
-
GC41381
CAY10562
4phenyl1,3,2Oxathiazolylium5olate
S-Nitrosothiols (RSNOs) are a class of molecules that function as exogenous and endogenous nitric oxide (NO) donors. -
GC52006
CB-096
An inhibitor of RAN translation
-
GC47100
Clevidipine-d7
rac-Clevidipine-d7
A neuropeptide with diverse biological activities -
GC47103
Clonidine-d4 (hydrochloride)
An internal standard for the quantification of clonidine
-
GC43399
Dehydro Amlodipine (fumarate)
Dehydro amlodipine is a potential impurity found in commercial preparations of amlodipine.
-
GC43405
Dehydroevodiamine (hydrochloride)
Dehydroevodiamine is an alkaloid that has been isolated from E.
-
GC49866
Desmethyl Carvedilol
BM 14242, O-desmethyl Carvedilol
An active metabolite of carvedilol -
GC46131
Diazoxide-d3
An internal standard for the quantification of diazoxide
-
GC45427
Dihydrolycorine
-
GC49497
Dopamine-d4 (hydrochloride)
DA-d4, 3-hydroxy Tyramine-d4
An internal standard for the quantification of dopamine -
GC47268
Doxazosin-d8 (hydrochloride)
An internal standard for the quantification of doxazosin
-
GC43601
Enalaprilat (hydrate)
Angiotensin-converting enzyme (ACE) converts angiotensin I to angiotensin II, a peptide hormone that impacts vascular smooth muscle tone and renal salt exchange, driving hypertension.
-
GC20107
Fendiline hydrochloride
Fendiline hydrochloride is a nonselective calcium channel blocker.
-
GC45761
Flupirtine-d4 (hydrochloride)
D 9998-d4 hydrochloride
Flupirtin-d4 (D 9998-d4) Hydrochlorid ist das mit Deuterium bezeichnete Flupirtin. -
GC47371
Fosinopril-d7 (sodium salt)
An internal standard for the quantification of fosinopril
-
GC49089
FR900359
UBO-QIC
FR900359 ist ein Inhibitorder G-Proteine Gαq, Gα11, and Gα14with IC50 values of 13.18, 10.47 bzw. 10nM und wird aus den Blättern der Zierpflanze Ardisia crenata isoliert. -
GC49117
Guanadrel
Guanadrel ist ein oral aktiver postganglionÄrer adrenerger Inhibitor von Spiroketal.
-
GC47418
Gymnoascolide A
A fungal metabolite with fungicidal and vasodilatory activities
-
GC46155
H-Ile-Pro-Pro-OH (trifluoroacetate salt)
IPP
A neuropeptide with diverse biological activities -
GC47438
H-Val-Pro-Pro-OH (trifluoroactetate salt)
VPP
A neuropeptide with diverse biological activities -
GC43802
HA-1004 (hydrochloride)
HA-1004 is an inhibitor of protein kinase G (PKG) and PKA (Kis = 1.4 and 2.3 μM, respectively).
-
GC43803
HA-1077 (hydrochloride)
Fasudil
Fasudil (HA-1077; AT877) dihydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μ ;M, 1.650 μM fÜr ROCK2 bzw. PKA, PKC, PKG. HA-1077 (Hydrochlorid) ist auch ein potenter Ca2+-Kanalantagonist und Vasodilatator. -
GC49882
Hemokinin 1 (human) (trifluoroacetate salt)
HK-1, TGKASQFFGLM-NH2, Thr-Gly-Lys-Ala-Ser-Gln-Phe-Phe-Gly-Leu-Met-NH2
A peptide agonist of NK1 receptors -
GC47439
Hydralazine-d4 (hydrochloride)
1-Hydrazinophthalazine-d4
A neuropeptide with diverse biological activities -
GC49343
Isoproterenol-d7 (hydrochloride)
Isoprenaline-d7
An internal standard for the quantification of isoproterenol -
GC47471
Isoxsuprine-d6 (hydrochloride)
A neuropeptide with diverse biological activities
-
GC52310
L-Arginine-13C6 (hydrochloride)
L-(+)-Arginine-13C6
An internal standard for the quantification of L-arginine -
GC49374
L-Arginine-d7 (hydrochloride)
L-(+)-Arginine-d7
L-Arginin-d7 ((S)-(+)-Arginin-d7) Hydrochlorid ist das mit Deuterium markierte L-Arginin-Hydrochlorid. -
GC44062
L-hydroxy Arginine (acetate)
L-NG-hydroxy Arginine, N5-hydroxy L-Arginine, Nω-hydroxy-L-Arginine
L-hydroxy Arginine is a substrate for nitric oxide synthase in the catabolism of L-arginine to form nitric oxide. -
GC40239
Limaprost-d3
17α,20-dimethyl-Δ2-PGE1-d3, 17α,20-dimethyl-Δ2-Prostaglandin E1-d3
Limaprost-d3 is intended for use as an internal standard for the quantification of limaprost by GC- or LC-MS. -
GC47585
Lys-(Des-Arg9)-Bradykinin (trifluoroacetate salt)
(Des-Arg10)-Kallidin, (Des-Arg10)-KD, KRPPGFSPF-OH, Lys-(Des-Arg9)-BK, N2-L-lysyl-9-de-L-arginine-Bradykinin
A neuropeptide with diverse biological activities -
GC49916
Lys-(Des-Arg9, Leu8)-Bradykinin (trifluoroacetate salt)
Des-Arg10,Leu9-Kallidin, Des-Arg10,Leu9-KD, LysLeu8Des-Arg9-BK, LysLeu8Des-Arg9-Bradykinin
A bradykinin B1 receptor antagonist -
GC40231
Milrinone-d3
Milrinone-d3 is intended for use as an internal standard for the quantification of milrinone by GC- or LC-MS.
-
GC47679
Minoxidil-d10
Loniten-d10, U-10858-d10
An internal standard for the quantification of minoxidil -
GC92012
MT-1207 (hydrochloride)
MT-1207 (hydrochloride) ist ein oral aktiver und selektiver adrenerger α1- und 5-HT2A-Rezeptorantagonist. MT-1207 zeigt IC50<0.1 nM, 0.15 nM, 1.40 nM und 0.27 nM für α1A, α1B, α1D und 5-HT2A.
-
GC44320
N-Arachidonoyl-L-Serine
ARA-S
Arachidonoyl amides of both amino acids and neurotransmitters such as dopamine have been previously reported in the literature. -
GC49683
N-desethyl-N-methyl Vardenafil
A potential impurity found in commercial preparations of vardenafil
-
GC52045
N-desmethyl Azelastine
DAZ, Desmethylazelastine
N-Desmethylazelastin ist ein aktiver Hauptmetabolit von Azelastin, der durch das Cytochrom-P450-Enzymsystem mit einer Proteinbindungsrate von 97 % und einer Eliminationshalbwertszeit von 54 Stunden oxidativ metabolisiert wird. -
GC52132
N-desmethyl Diltiazem (hydrochloride)
-
GC44351
N-Desmethyl Sildenafil (citrate)
N-Desmethyl sildenafil is a major metabolite of sildenafil.
-
GC48584
Naftopidil-d5
KT-611-d5; BM-15275-d5
-
GC44358
Nebivolol O-β-D-Glucuronide
Nebivolol O-β-D-glucuronide is an active metabolite of the β1-adrenergic receptor antagonist nebivolol.
-
GC49301
Nesiritide (acetate)
A natriuretic peptide