Ophthalmology
Produkte für Ophthalmology
- Bestell-Nr. Artikelname Informationen
- GC49769 β-Glucogallin A plant metabolite and an aldose reductase 2 inhibitor
- GC41197 (±)17-HDHA (±)17-HDHA is an autoxidation product of docosahexaenoic acid in vitro.
- GC45979 1-Palmitoyl-2-Oleoyl-3-Arachidonoyl-rac-glycerol A triacylglycerol
- GC46412 11β-Prostaglandin F2α-d4 An internal standard for the quantification of 11β-PGF F2α
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GC18798
11-cis Retinal
11-cis Retinal is a chromophore that binds to opsin in the mammalian visual system as an inverse agonist forming the inactive conformation of rhodopsin.
- GC48821 11-cis Retinol An isomer of vitamin A
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GC18637
11β-Prostaglandin F2α
11β-Prostaglandin F2α (11β-PGF2α) is the primary plasma metabolite of PGD2 in vivo.
- GC49808 12-methyl Tridecanoic Acid A methylated fatty acid
- GC40988 15(R)-17-phenyl trinor Prostaglandin F2α 17-phenyl trinor Prostaglandin F2α N-ethyl amide (17-phenyl trinor PGF2α) is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name 17-phenyl trinor PGF2α ethyl amide.
- GC41922 15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester 15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester (15(R)-17-phenyl trinor PGF2α isopropyl ester) is the latanoprost-related isomer containing both a double bond at 13,14 and an inverted (β) hydroxyl group at C-15.
- GC41093 15(S)-Latanoprost 15(S)-Latanoprost is an analog of latanoprost in which the hydroxyl at carbon 15 is inverted relative to latanoprost.
- GC49036 15-(6-nitroxyhexanoyl)-17-phenyl trinor Prostaglandin F2α A nitric oxide-donating derivative of 17-phenyl trinor prostaglandin F2α
- GC41934 15-keto Latanoprost 15-Keto-Latanoprost ist ein Metabolit von Latanoprost, einem augendrucksenkenden Mittel.
- GC40989 15-keto Latanoprost (free acid) 15-keto Latanoprost is a potential metabolite of latanoprost when administered to animals.
- GC41936 15-keto-17-phenyl trinor Prostaglandin F2α Bimatoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug.
- GC41937 15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide), an F-series PG analog which has been approved for use as an ocular hypotensive drug.
- GC41947 16-phenoxy tetranor Prostaglandin F2α cyclopropyl methyl amide The actions of many clinical F-series prostaglandins (PGs), including those used for estrous synchronization and for reduction of intraocular pressure (IOP), are mediated through the PGF2α (FP) receptor.
- GC41948 16-phenoxy tetranor Prostaglandin F2α isopropyl ester Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor.
- GC40961 16-phenoxy tetranor Prostaglandin F2α methyl ester Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor.
- GC40990 17-phenyl trinor Prostaglandin F2α 17-phenyl trinor Prostaglandin F2α (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor.
- GC41967 17-phenyl trinor Prostaglandin F2α amide 17-Phenyltrinor Prostaglandin F2α Amid ist ein N-Desethyl-Metabolit von Bimatoprost.
- GC41969 17-phenyl trinor Prostaglandin F2α cyclopropyl amide 17-phenyl trinor Prostaglandin F2α cyclopropyl amide (17-phenyl trinor PGF2α cyclopropyl amide) is a novel analog of 17-phenyl trinor PGF2α ethyl amide.
- GC41970 17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide Prostaglandin F2α (PGF2α) activates the FP receptor, promoting smooth muscle contraction and luteolysis.
- GC41971 17-phenyl trinor Prostaglandin F2α diethyl amide 17-phenyl trinor Prostaglandin F2α diethyl amide (17-phenyl trinor PGF2α diethyl amide) is an analog of PGF2α in which the C-1 carboxyl group has been modified to an N-diethyl amide.
- GC46458 17-phenyl trinor Prostaglandin F2α dimethyl amide An isomer of 17-phenyl trinor prostaglandin F2α ethyl amide
- GC41972 17-phenyl trinor Prostaglandin F2α isopropyl ester 17-phenyl trinor PGF2α N-ethyl amide is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name Bimatoprost.
- GC41973 17-phenyl trinor Prostaglandin F2α methyl amide 17-phenyl trinor Prostaglandin F2α (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor, binding with a relative potency of 756% compared to that of PGF2α.
- GC40392 17-phenyl trinor Prostaglandin F2α methyl ester 17-Phenyltrinor Prostaglandin F2α Methylester ist ein Prodrug von Bimatoprost.
- GC46463 17-phenyl trinor Prostaglandin F2α-d4 An internal standard for the quantification of bimatoprost (free acid)
- GC41975 17-trifluoromethylphenyl trinor Prostaglandin F2α A number of 17-phenyl trinor prostaglandin F2α (17-phenyl trinor PGF2α) derivatives have been approved for the treatment of glaucoma.
- GC41976 17-trifluoromethylphenyl trinor Prostaglandin F2α ethyl amide Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity.
- GC41978 17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity.
- GC46466 17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α A prostaglandin F derivative similar to latanoprost free acid
- GC49671 2,3-Oxidosqualene An intermediate in the biosynthesis of sterols
- GC52324 3-(3-Hydroxyphenyl)propionic Acid sulfate A metabolite of certain phenols and glycosides
- GC52129 3-Amino-5-hydroxybenzoic Acid
- GC49244 4-oxo Isotretinoin An active metabolite of isotretinoin
- GC18582 5'-hydroxy Meloxicam A metabolite of meloxicam
- GC41094 5-trans Latanoprost Latanoprost is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug.
- GC41228 5-trans Latanoprost (free acid) Latanoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug.
- GC49438 5-trans-17-phenyl trinor Prostaglandin F2α The 5-trans isomer of 17-phenyl trinor PGF2α
- GC40572 7-keto Cholesterol 7-Keto-Cholesterin, giftiges Oxysterin, hemmt den geschwindigkeitsbestimmenden Schritt in der Gallensäure-Biosynthese, Cholesterin 7-alpha-Hydroxylase, sowie stark inhibierende HMG-CoA-Reduktase (das geschwindigkeitsbestimmende Enzym in der Cholesterin-Biosynthese).
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GC46241
7-keto Cholesterol-d7
7-keto Cholesterol is a bioactive sterol and a major oxysterol component of oxidized LDL
- GC42760 AL 6598 Elevated intraocular pressure (IOP) is an important risk factor in developing glaucoma.
- GC42761 AL 8810 ethyl amide AL 8810 is an 11β-fluoro analog of prostaglandin F2α (PGF2α) which acts as a potent and selective antagonist at the FP receptor.
- GC46922 Betamethasone 21-phosphate (sodium salt hydrate) A synthetic glucocorticoid
- GC42973 Brain-Derived Basic Fibroblast Growth Factor (1-24) (bovine) (trifluoroacetate salt) Brain-derived basic fibroblast growth factor (1-24) (brain-derived bFGF) is a peptide fragment of brain-derived bFGF.
- GC40077 Brimonidine-d4 Brimonidine-d4 is intended for use as an internal standard for the quantification of brimonidine by GC- or LC-MS.
- GC46101 Brinzolamide-d5 An internal standard for the quantification of brinzolamide
- GC43034 C16 Phytoceramide (t18:0/16:0) C16 Phytoceramide (t18:0/16:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis.
- GC18315 Calpain Inhibitor VI Calpain inhibitor VI is an inhibitor of the calcium-dependent cysteine proteases u-calpain (calpain-1; IC50 = 7.5 nM) and m-calpain (calpain-2; IC50 = 78 nM).
- GC47053 CAY10746 A ROCK1 and ROCK2 inhibitor
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GC43254
Cholesteryl Arachidate
Cholesteryl arachidate is a cholesterol ester that has been found in human meibum.
- GC40042 Cholesteryl Erucate Cholesteryl erucate is a cholesterol ester.
- GC40041 Cholesteryl Lignocerate Cholesteryl lignocerate is a cholesterol ester that has been found in human meibum.
- GC49726 Cholesteryl Nervonate A cholesterol ester
- GC49709 cyclo(RGDyC) (trifluoroacetate salt) A cyclic pentapeptide
- GC49913 Davunetide (acetate) A neuroprotective ADNP-derived peptide
- GC47210 Dichlorphenamide-13C6 An internal standard for the quantification of dichlorphenamide
- GC52120 DMPE-MPEG(2000) A PEGylated form of DMPE
- GC18648 Echothiophate (iodide) Echothiophat (Iodid) ist ein potenter hBChE (humane Butyrylcholinesterase)-Hemmer.
- GC49063 Emedastine-13C-d3 (fumarate) An internal standard for the quantification of emedastine
- GC43693 Fluprostenol serinol amide 2-arachidonyl glycerol (2-AG) exhibits cannabinoid (CB) agonist activity at the CB1 receptor, is an important endogenous monoglyceride species, and is thus considered to be the natural ligand for the CB1 receptor.
- GC49416 Gap 27 (trifluoroacetate salt) A connexin-mimetic peptide
- GC43740 GAT229 GAT229 is a positive allosteric modulator of cannabinoid receptor 1 (CB1) and the S-(-) enantiomer of the CB1 modulator GAT211.
- GC40191 Ibuprofen Carboxylic Acid Ibuprofen carboxylic acid is a major metabolite of ibuprofen.
- GC47454 IMS 2186 An anti-choroidal neovascularization agent
- GC48621 INNO-8875 INNO-8875 (INO-8875), ein Adenosin-Mimetikum, ist ein hochselektiver Adenosin-A1-Rezeptor-Agonist.
- GC49600 Isopropyl 5-(Diphenylphosphoryl)pentanoate A potential impurity in latanoprost preparations
- GC47528 Ketorolac (calcium salt) Ketorolac (RS37619) Hemicalcium ist ein nichtsteroidales Antirheumatikum (NSAID), das als nichtselektiver COX-Hemmer mit IC50-Werten von 20 nM fÜr COX-1 und 120 nM fÜr COX-2 wirkt.
- GC47532 KUS121 A VCP modulator
- GC52328 KYL (trifluoroacetate salt) An EphA4 inhibitor
- GC47539 Latanoprost (free acid)-d4 Internal standard for the quantification of latanoprost (free acid)
- GC47540 Latanoprost amide A derivative of latanoprost
- GC47541 Latanoprost dimethyl amide A derivative of latanoprost
- GC44037 Latanoprost ethyl amide Latanoprost ethyl amide (Lat-NEt) is a latanoprost analog in which the C-1 carboxyl group has been modified to an N-ethyl amide.
- GC52264 Latanoprost tris(triethylsilyl) ether A precursor in the synthesis of latanoprost
- GC44092 Lumula There are currently four prostaglandin (PG) derivatives which have been approved for human clinical use for the treatment of glaucoma.
- GC44093 Lutein Lutein is a natural yellow carotenoid, which can be found in plants, egg yolks, and in the human retina.
- GC48889 Methazolamide-d6 An internal standard for the quantification of methazolamide
- GC48661 Methylatropine (nitrate) A muscarinic acetylcholine receptor antagonist
- GC52419 MOG (35-55) (mouse, rat) (trifluoroacetate salt) An MOG antigen peptide
- GC49210 N-desethyl Brinzolamide (oxalate) An active metabolite of brinzolamide
- GC17636 Noladin ether Noladinether ist ein potenter und selektiver Agonist des Cannabinoid-CB1-Rezeptors mit einem Ki von 21,2 nM.
- GC49211 O-desmethyl Brinzolamide (hydrochloride) An active metabolite of brinzolamide
- GC47825 Olopatadine-d3 (hydrochloride) An internal standard for the quantification of olopatadine
- GC47850 Oxybutynin-d10 (hydrochloride) An internal standard for the quantification of oxybutynin
- GC18332 Oxyphenonium (bromide) Oxyphenonium is an antagonist of muscarinic acetylcholine receptors that binds to muscarinic receptors on isolated guinea pig atria and ileum (Kds = 0.11 and 0.17 nM, respectively).
- GC49422 PAR2 (1-6) amide (human) (trifluoroacetate salt) A peptide agonist of PAR2
- GC52270 Pranoprofen-13C-d3 An internal standard for the quantification of pranoprofen
- GC40610 Prostaglandin D3 Prostaglandin D3 (PGD3) is produced by the metabolism of EPA via the COX pathway.
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GC40611
Prostaglandin E3
Prostaglandin E3 (PGE3) is formed via the cyclooxygenase (COX) metabolism of eicosapentaenoic acid.
- GC40401 Prostaglandin F2α Alcohol methyl ether Prostaglandin F2α alcohol methyl ether (PGF2α-OMe) is an analog of PGF2α in which the C-1 carboxyl group has been replaced an O-methyl ether.
- GC41407 Prostaglandin F2α Ethanolamide Prostaglandin F2α ethanolamide (PGF2α-EA) is produced by COX-2 metabolism of the endogenous cannabinoid, arachidonoyl ethanolamide (AEA), found in brain, liver, and other mammalian tissues.
- GC44723 Prostaglandin F2α ethyl amide Prostaglandin F2α ethyl amide (PGF2α-NEt) is an analog of PGF2α in which the C-1 carboxyl group has been modified to an N-ethyl amide.
- GC44724 Prostaglandin F2α isopropyl ester PGF2α isopropyl ester is an ester prodrug of PGF2α with enhanced lipid solubility.
- GC18914 Prostaglandin F2α Alcohol Prostaglandin F2α alcohol (PGF2α-OH) is an analog of PGF2α in which the C-1 carboxyl group has been reduced to a primary alcohol.
- GC18370 Prostaglandin F2α methyl ester Prostaglandin F2α methyl ester (PGF2α methyl ester) is an analog of PGF2α in which the C-1 carboxyl group has been esterified as the methyl ester.
- GC49203 rac-Desethyl Oxybutynin (hydrochloride) An active metabolite of oxybutynin
- GC48401 Risuteganib (trifluoroacetate salt) An anti-integrin peptide