Pain Research
Produkte für Pain Research
- Bestell-Nr. Artikelname Informationen
- GC49097 α-Conotoxin AuIB (trifluoroacetate salt) A conotoxin and an antagonist of α3β4 subunit-containing nAChRs
- GC41499 α-Phellandrene α-Phellandrene is a cyclic monoterpene that has been found in various plants, including Cannabis, and has diverse biological activities.
- GC45234 β-Endorphin (1-27) (human) (trifluoroacetate salt) β-Endorphin (1-27) is an endogenous peptide that binds to μ-, δ-, and κ-opioid receptors (Kis = 5.31, 6.17, and 39.82 nM, respectively, in COS-1 cells expressing rat receptors).
- GC49865 γ-D-Glutamylglycine (trifluoroacetate salt) An excitatory amino acid antagonist
- GC46288 (±)-Epibatidine (hydrochloride) An agonist of α4β2 subunit-containing nAChRs
- GC49515 (±)-Ibuprofen-d3 (sodium salt) An internal standard for the quantification of (±)-ibuprofen
- GC41685 (±)-WIN 55,212 (mesylate) (±)-WIN 55,212-2 is a potent aminoalkylindole cannabinoid (CB) receptor agonist with a Ki value of 62.3 and 3.3 nM for human recombinant central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, respectively.
- GC41191 (±)13(14)-EpDPA (±)13(14)-EpDPA (13,14-EpDPE) ist das Produkt der Reaktion von Cytochrom-P-450-Epoxygenase mit Docosahexaensäure (DHA).
- GC41203 (±)7(8)-EpDPA Docosahexaenoic acid is the most abundant ω-3 fatty acid in neural tissues, especially in the brain and retina.
- GC18343 (-)-CP 55,940 (-)-CP 55,940 is a potent and non-selective cannabinoid (CB) receptor agonist with Ki values of 0.5 to 5 and 0.69 to 2.8 nM for CB1 and CB2 receptors, respectively.
- GC40594 (R)-AM1241 (R)-AM1241 binds to cannabinoid (CB) receptors and has greater than 100-fold selectivity for the CB2 over the CB1 receptor (Kis = 15 and 5,000 nM, respectively, in a membrane assay using human receptors).
- GC40595 (S)-AM1241 (S)-AM1241 binds to cannabinoid (CB) receptors and is selective for the CB2 over the CB1 receptor (Kis = 658 and >10,000 nM, respectively, in a membrane assay using human receptors).
- GC46366 1,2,3,4-Tetrahydro-β-carboline A serotonin reuptake inhibitor and metabolite of tryptamine
- GC49861 1-Carboxycyclohexaneacetic Acid A potential impurity in commercial preparations of gabapentin
- GC46050 1-Deoxysphingosine (m18:1(4E)) An atypical sphingolipid
- GC18783 13,14-dihydro-15-keto Prostaglandin E1 13,14-dihydro-15-keto Prostaglandin E1 (PGE1) is a metabolite of PGE1 with much reduced biological activity.
- GC42258 3-Cysteinylacetaminophen (trifluoroacetate salt) An acetaminophen-protein adduct
- GC49752 4,5-Desisopropylidene Topiramate An inactive metabolite of topiramate
- GC18582 5'-hydroxy Meloxicam A metabolite of meloxicam
- GC49119 5-hydroxy Flunixin A metabolite of flunixin
- GC42550 5-hydroxy-6-methoxy (S)-Duloxetine 5-hydroxy-6-methoxy (S)-Duloxetine is a metabolite of (S)-duloxetine.
-
GC42580
6-hydroxy Chlorzoxazone
6-hydroxy Chlorzoxazone is a metabolite of chlorzoxazone.
- GC48880 7-Methoxyflavone 7-Methoxyflavon ist eine aus Zornia brasiliensis isolierte Verbindung.
-
GC40759
8-methyl Nonanoic Acid
Capsaicin, the chemical that imparts the spicy-hot quality of chili peppers, is produced by the fruits of plants belonging to the Capsicum family.
- GC42693 Acetaminophen Glucuronide (sodium salt) Acetaminophen glucuronide is an inactive metabolite of the analgesic and antipyretic agent acetaminophen.
- GC42694 Acetaminophen sulfate (potassium salt) Acetaminophen sulfate is a metabolite of acetaminophen.
- GC46781 Acetaminophen-d4 A Certified Reference Material
- GC42704 Acetyl β-Endorphin (human) (trifluoroacetate salt) Acetyl β-endorphin is an acetylated derivative of β-endorphin that binds to opioid receptors in rat caudal dorsomedial medulla (Ki = 490 nM) and mouse brain membrane preparations (IC50 = 109 nM).
- GC46789 Acetyl-L-carnitine-d3 (chloride) An internal standard for the quantification of L-acetylcarnitine
- GC49639 Akuammine An indole alkaloid with analgesic activity
- GC46826 Alclofenac An NSAID
-
GC42809
Angiotensin II (3-8) (human, rat, mouse) (trifluoroacetate salt)
Angiotensin II (3-8) is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin II.
-
GC46856
Angiotensin II (5-8) (human, rat, mouse) (trifluoroacetate salt)
An endogenous angiotensin II fragment
- GC46858 Anthirine An alkaloid with analgesic activity
- GC49473 ARA 290 (acetate) A derivative of EPO
- GC46877 Arachidonoyl Glycine-d8 An internal standard for the quantification of arachidonoyl glycine
- GC42865 AT-121 AT-121 ist ein bifunktionaler Nozizeptions- und Mu-Opioidrezeptor-Agonist mit einem Kis von 3,67 bzw. 16,49 nM.
- GC42885 AX 048 The group IVA phospholipase A2 (PLA2), known as calcium-dependent cytosolic PLA2 (cPLA2), selectively releases arachidonic acid from membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins and leukotrienes.
- GC52409 BAM-22P (8-22) (human, mouse, rat, bovine) (trifluoroacetate salt) A neuropeptide and MRGPRX1 agonist
- GC52407 BAM-22P (human, mouse, rat, bovine) (trifluoroacetate salt) A neuropeptide
- GC49019 BAN ORL 24 (hydrochloride) A nociceptin receptor antagonist
- GC39344 BAY-1797 BAY-1797 ist ein potenter, oral aktiver und selektiver P2X4-Antagonist mit einem IC50-Wert von 211 nM gegen humanes P2X4.
- GC49836 Benoxaprofen Benoxaprofen (LRCL 3794) ist eine starke und lang wirkende entzÜndungshemmende und fiebersenkende Verbindung.
- GC49300 BIM-46187 (hydrochloride) An inhibitor of heterotrimeric G-protein signaling
- GC52145 Bradykinin (human, mouse, rat, bovine) (acetate)
- GC49880 Bradykinin (trifluoroacetate salt) An endogenous vasodilator
- GC52424 Bradykinin Fragment (1-5) (trifluoroacetate salt) A metabolite of bradykinin
- GC42990 Bupivacaine Bupivacain ist ein NMDA-Rezeptor-Inhibitor.
- GC46959 Bupivacaine-d9 Bupivacain-d9 ist ein Deuterium mit der Bezeichnung Bupivacain.
- GC49761 Capsaicin-d3 Capsaicin-d3 ((E)-Capsaicin-d3) ist das mit Deuterium bezeichnete Capsaicin. Capsaicin ((E)-Capsaicin), ein aktiver Bestandteil von Chilischoten, ist ein TRPV1-Agonist. Capsaicin hat schmerzlindernde, antioxidative, entzÜndungshemmende, neuroprotektive und krebshemmende Wirkungen.
- GC49433 Capsiate Capsiat, als ein Capsaicin-Analogon, das aus einer nicht scharfen Sorte von CH-19-SÜßpaprika extrahiert wird, ist ein oral aktiver Agonist von TRPV1.
- GC43155 CAY10448 Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper.
- GC43171 CAY10568 Most local anesthetics act by abolishing voltage gated sodium channel currents indiscriminately in all populations of neurons.
- GC49226 CAY10787 An oxysterol and a negative allosteric modulator of GABAA receptors
- GC18695 CB-86 CB-86 is a resorcinol-anandamide hybrid compound that acts as a partial agonist for the central cannabinoid (CB1) receptor and a neutral antagonist for the peripheral cannabinoid (CB2) receptor with Ki values of 5.6 and 7.9 nM, respectively.
- GC52438 CGRP (8-37) (mouse, rat) (trifluoroacetate salt) A CGRP receptor antagonist
- GC49191 Chlorzoxazone-d3 An internal standard for the quantification of chlorzoxazone
- GC18369 Cimicoxib Cimicoxib (CX) ist ein oral aktiver potenter und selektiver COX-2 (Cyclooxygenase-2)-Hemmer.
- GC18728 CJ-13610 CJ-13610, ein Nicht-Redox-Typ-5-LO-Inhibitor, unterdrückt dosisabhängig die 5-LO-Produktbildung in Ionophor A23187-stimulierter PMNL in Abwesenheit von exogenem AA mit einem IC50 von etwa 70 nM.
- GC52243 Corynantheidine An alkaloid with antinociceptive activity
- GC43327 CTAP (trifluoroacetate salt) CTAP is a water soluble, cyclic octapeptide which acts as a receptor antagonist that is selective for the μ opioid receptor (IC50 = 3.5 nM) over the δ receptor (IC50 = 4,500 nM).
- GC52077 CTP354 CTP354 ist das mit L-838417 bezeichnete Deuterium.
- GC43373 D-Amino Acid Oxidase Inhibitor D-Amino acid oxidase inhibitor is an inhibitor of D-amino acid oxidase (DAAO) with IC50 values of 145 and 114 nM in CHO cells expressing human and rat DAAO, respectively.
- GC43383 DBO-83 DBO-83 is an agonist of nicotinic acetylcholine receptors (nAChRs) with antinociceptive and anti-amnesic activities.
- GC43391 Decanoic Acid (sodium salt) Decanoic acid is a saturated medium-chain fatty acid that contains 10 carbons.
- GC45815 Decanoic Acid-d19 An internal standard for the quantification of decanoic acid
- GC46127 Decanoic Acid-d2 An internal standard for the quantification of decanoic acid
- GC45722 Decanoic Acid-d3 An internal standard for the quantification of decanoic acid
- GC49338 Deltorphin II (trifluoroacetate salt) A peptide agonist of δ2-opioid receptors
- GC47188 Dermorphin (acetate) An opioid peptide
- GC49858 Desipramine-d4 (hydrochloride) An internal standard for the quantification of desipramine
- GC47212 Diclofenac amide A prodrug form of diclofenac
- GC43446 Diclofenac ethyl ester An esterified form of diclofenac
- GC43447 Diclofenac methyl ester Diclofenac methyl ester is a hydrophobic prodrug form of the non-steroidal anti-inflammatory drug (NSAID) diclofenac.
- GC49304 Difelikefalin (trifluoroacetate salt) A κ-opioid receptor agonist
- GC49829 DL-threo-β-Hydroxyaspartic Acid An EAAT inhibitor
- GC47314 Ethopropazine (hydrochloride) Ethopropazin (Isothazin)-Hydrochlorid ist ein starker, selektiver BChE-Hemmer und ein schwacher AChE-Hemmer.
- GC47323 Etofenamate-d4 An internal standard for the quantification of etofenamate
- GC47336 Fenobam (hydrate) A noncompetitive antagonist and inverse agonist of mGluR5
- GC49747 Flunixin-d3 An internal standard for the quantification of flunixin
- GC45761 Flupirtine-d4 (hydrochloride) Flupirtin-d4 (D 9998-d4) Hydrochlorid ist das mit Deuterium bezeichnete Flupirtin.
- GC47388 Gabapentin-d4 An internal standard for the quantification of gabapentin
- GC49154 Galanin (2-11) amide (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) A synthetic peptide fragment of galanin and an agonist of the GAL2 receptor
- GC48326 Galanin (human) (acetate) A neuropeptide and GAL receptor agonist
-
GC43724
Galanin (rat, mouse) (trifluoroacetate salt)
Galanin is a neuropeptide with diverse biological activities.
- GC43738 GAT211 GAT211 ist ein Cannabinoid-1-Rezeptor (CB1R) positiver allosterischer Modulator (PAM).
- GC43774 Glycerophospho-N-Arachidonoyl Ethanolamine N-Acylated ethanolamines (NAE) are naturally-occurring lipids that have diverse bioactivities.
- GC49509 Glycyl-L-Glutamine (hydrate) A dipeptide fragment of β-endorphin
- GC18181 GW 405833 GW 405833 (L768242) ist ein potenter, selektiver Cannabinoidrezeptor 2 (CB2)-Agonist mit einem EC50 von 50,7 nM.
- GC49882 Hemokinin 1 (human) (trifluoroacetate salt) A peptide agonist of NK1 receptors
- GC48453 Hodgkinsine An alkaloid with analgesic activity
- GC48454 Hodgkinsine B An alkaloid with analgesic activity
- GC49559 Hydroxymethyl Tolperisone (hydrochloride) A metabolite of tolperisone
- GC43891 IDFP The endocannabinoids, 2-arachidonoyl glycerol (2-AG) and arachidonoyl ethanolamide (AEA), are biologically active lipids that regulate diverse neurological and metabolic functions by activating the cannabinoid receptors, central cannabinoid (CB1) and peripheral cannabinoid (CB2).
- GC52154 Inflammasome Inhibitor 4b
- GC43906 Iperoxo (iodide) Iperoxo (Iodid) ist ein starker Superagonist des muskarinischen Acetylcholinrezeptors (mAChR).
- GC47528 Ketorolac (calcium salt) Ketorolac (RS37619) Hemicalcium ist ein nichtsteroidales Antirheumatikum (NSAID), das als nichtselektiver COX-Hemmer mit IC50-Werten von 20 nM fÜr COX-1 und 120 nM fÜr COX-2 wirkt.
- GC52020 Lamotrigine-d3 An internal standard for the quantification of lamotrigine
- GC49608 Larixyl Acetate Larixylacetat ist ein potenter und selektiver TRPC6-Inhibitor mit IC50-Werten von 0,58 μM und 6,83 μM gegen hTRPC6-YFP bzw. hTRPC3-YFP.
- GC49720 Leu-Enkephalin (trifluoroacetate salt) A neuropeptide and δ- and µ-opioid receptor agonist