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Startseite >> Signaling Pathways >> Cell Cycle/Checkpoint >> Proteolysis

Proteolysis

Produkte für  Proteolysis

  1. Bestell-Nr. Artikelname Informationen
  2. GC41656 (±)2-(14,15-Epoxyeicosatrienoyl) Glycerol 2-Arachidonoyl glycerol (2-AG) is an endogenous central cannabinoid (CB1) receptor agonist that is present at relatively high levels in the central nervous system. (±)2-(14,15-Epoxyeicosatrienoyl) Glycerol Chemical Structure
  3. GC40145 (S)-Laudanosine (S)-Laudanosine is the (S) enantiomer of laudanosine, a metabolite of the neuromuscular blocking agents atracurium and cisatracurium. (S)-Laudanosine Chemical Structure
  4. GC49390 13C6-4-Nitroaniline An internal standard for the quantification of 4-nitroaniline 13C6-4-Nitroaniline Chemical Structure
  5. GC18359 4-Epianhydrochlortetracycline (hydrochloride) 4-Epianhydrochlortetracycline is a derivative of tetracycline . 4-Epianhydrochlortetracycline (hydrochloride) Chemical Structure
  6. GC52227 5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone An active metabolite of various polyphenols 5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone Chemical Structure
  7. GC41423 5-trans Prostaglandin E2 5-trans PGE2 occurs naturally in some gorgonian corals and is a common impurity in commercial lots of PGE1. 5-trans Prostaglandin E2 Chemical Structure
  8. GC40202 7α-hydroxy Cholesterol-d7

    7α-hydroxy Cholesterol-d7 is intended for use as an internal standard for the quantification of 7α-hydroxy cholesterol by GC- or LC-MS.

     7α-hydroxy Cholesterol-d7 Chemical Structure
  9. GC42665 AAF-CMK (trifluoroacetate salt) Tripeptidyl peptidase II (TPPII) is a serine peptidase of the subtilisin-type which removes tripeptides from the free NH2 terminus of oligopeptides. AAF-CMK (trifluoroacetate salt) Chemical Structure
  10. GC42683 Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp is a fluorescence-quenched peptide substrate for human neutrophil elastase (kcat/Km = 531 mM-1s-1). Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp Chemical Structure
  11. GC52499 Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp (trifluoroacetate salt) A sensitive substrate for neutrophil elastase Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp (trifluoroacetate salt) Chemical Structure
  12. GC42684 Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp (trifluoroacetate salt) Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp is a fluorescence-quenched peptide substrate for human proteinase 3 (kcat/Km = 1,570 mM-1s-1). Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp (trifluoroacetate salt) Chemical Structure
  13. GA20494 Ac-Asp-Glu-Val-Asp-pNA The cleavage of the chromogenic caspase-3 substrate Ac-DEVD-pNA can be monitored at 405 nm. Ac-Asp-Glu-Val-Asp-pNA Chemical Structure
  14. GC48470 Ac-DEVD-CHO (trifluoroacetate salt) A dual caspase3/caspase7 inhibitor Ac-DEVD-CHO (trifluoroacetate salt) Chemical Structure
  15. GC42689 Ac-DNLD-AMC Ac-WLA-AMC ist ein fluorogenes Substrat von Caspase-3. Ac-DNLD-AMC Chemical Structure
  16. GC49704 Ac-FLTD-CMK (trifluoroacetate salt) An inhibitor of caspase-1, -4, -5, and -11 Ac-FLTD-CMK (trifluoroacetate salt) Chemical Structure
  17. GC18226 Ac-LEHD-AMC (trifluoroacetate salt) Ac-LEHD-AMC (Trifluoracetatsalz) ist ein fluorogenes Substrat fÜr Caspase-9 (Anregung: 341 nm; Emission: 441 nm). Ac-LEHD-AMC (trifluoroacetate salt) Chemical Structure
  18. GC40556 Ac-LETD-AFC Ac-LETD-AFC ist ein Caspase-8-fluorogenes Substrat. Ac-LETD-AFC Chemical Structure
  19. GC13400 Ac-VDVAD-AFC Ac-VDVAD-AFC ist ein Caspase-spezifisches fluoreszierendes Substrat. Ac-VDVAD-AFC kann Caspase-3-Ähnliche AktivitÄt und Caspase-2-AktivitÄt messen und kann fÜr die Erforschung von Tumoren und Krebs verwendet werden. Ac-VDVAD-AFC Chemical Structure
  20. GC52372 Ac-VDVAD-AFC (trifluoroacetate salt) A fluorogenic substrate for caspase-2 Ac-VDVAD-AFC (trifluoroacetate salt) Chemical Structure
  21. GC48974 Ac-VEID-AMC (ammonium acetate salt) A caspase-6 fluorogenic substrate Ac-VEID-AMC (ammonium acetate salt) Chemical Structure
  22. GC18021 Ac-YVAD-CHO Ac-YVAD-CHO (L-709049) ist ein potenter, reversibler, spezifischer Tetrapeptid-Hemmer des Interleukin-lβ-Converting-Enzyms (ICE) mit Maus- und Human-Ki-Werten von 3,0 und 0,76 nM. Ac-YVAD-CHO Chemical Structure
  23. GC42721 Ac-YVAD-CMK

    Ac-YVAD-CMK ist ein selektiver, irreversibler Inhibitor von Caspase-1 (Ki=0,8nM), der die Aktivierung des proinflammatorischen Zytokins IL-1β verhindern kann. Ac-YVAD-CMK kann die Entzündungsreaktion reduzieren und einen lang anhaltenden neuroprotektiven Effekt auslösen.

     Ac-YVAD-CMK Chemical Structure
  24. GC42788 Aminopeptidase N Inhibitor Aminopeptidase N (AP-N) inhibitor is a reversible inhibitor of AP-N/CD13 (IC50 = 25 μM). Aminopeptidase N Inhibitor Chemical Structure
  25. GC46867 Apremilast-d5 Apremilast D5 (CC-10004 D5) ist ein Deuterium mit der Bezeichnung Apremilast. Apremilast-d5 Chemical Structure
  26. GC46878 Aranciamycin A fungal metabolite with diverse biological activities Aranciamycin Chemical Structure
  27. GC46895 Aurintricarboxylic Acid (ammonium salt) A protein synthesis inhibitor with diverse biological activities Aurintricarboxylic Acid (ammonium salt) Chemical Structure
  28. GC46937 Boc-Glu-OBzl An amino acid-containing building block Boc-Glu-OBzl Chemical Structure
  29. GC45394 Bz-IEGR-pNA (acetate)   Bz-IEGR-pNA (acetate) Chemical Structure
  30. GC18315 Calpain Inhibitor VI Calpain inhibitor VI is an inhibitor of the calcium-dependent cysteine proteases u-calpain (calpain-1; IC50 = 7.5 nM) and m-calpain (calpain-2; IC50 = 78 nM). Calpain Inhibitor VI Chemical Structure
  31. GC43150 CAY10406 CAY10406 is a trifluoromethyl analog of an isatin sulfonamide compound that selectively inhibits caspases 3 and 7. CAY10406 Chemical Structure
  32. GC43154 CAY10443 Mitochondrial release of cytochrome c triggers apoptosis via the assembly of a multimeric complex including caspase-9, Apaf-1, and other components, sometimes called the apoptosome. CAY10443 Chemical Structure
  33. GC47079 Chloramine-T (hydrate) A common reagent Chloramine-T (hydrate) Chemical Structure
  34. GC52360 Chymotrypsin Substrate I, Colorimetric (trifluoroacetate salt) A colorimetric chymotrypsin substrate Chymotrypsin Substrate I, Colorimetric (trifluoroacetate salt) Chemical Structure
  35. GC18421 Dabcyl-YVADAPV-EDANS Dabcyl-YVADAPV-EDANS is a fluorogenic substrate for caspase-1. Dabcyl-YVADAPV-EDANS Chemical Structure
  36. GC43371 Dabigatran Acyl-β-D-Glucuronide

    Dabigatran acyl-β-D-glucuronide is a major active metabolite of the thrombin inhibitor dabigatran.

     Dabigatran Acyl-β-D-Glucuronide Chemical Structure
  37. GC49684 Dabigatran-13C-d3 An internal standard for the quantification of dabigatran Dabigatran-13C-d3 Chemical Structure
  38. GC49682 Dabigatran-d3 An internal standard for the quantification of dabigatran Dabigatran-d3 Chemical Structure
  39. GC43545 Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2 Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1) and MMP-9. Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2 Chemical Structure
  40. GC43546 Dnp-PLALWAR (trifluoroacetate salt) Dnp-PLALWAR is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1) and MMP-8. Dnp-PLALWAR (trifluoroacetate salt) Chemical Structure
  41. GC43547 Dnp-PLAYWAR (trifluoroacetate salt) Dnp-PLAYWAR is a fluorogenic substrate for matrix metalloproteinase-8 (MMP-8) and MMP-26. Dnp-PLAYWAR (trifluoroacetate salt) Chemical Structure
  42. GC43550 Dnp-PLGMWSR (trifluoroacetate salt) Dnp-PLGMWSR is a fluorogenic substrate for matrix metalloproteinase-2 (MMP-2) and MMP-9. Dnp-PLGMWSR (trifluoroacetate salt) Chemical Structure
  43. GC43552 Dnp-RPLALWRS (trifluoroacetate salt) Dnp-RPLALWRS is a fluorogenic substrate for matrix metalloproteinase-7 (MMP-7). Dnp-RPLALWRS (trifluoroacetate salt) Chemical Structure
  44. GC43614 Enteropeptidase Fluorogenic Substrate Enteropeptidase fluorogenic substrate is a substrate for enteropeptidase that contains a 7-amino-4-trifluoromethylcoumarin (AFC) moiety. Enteropeptidase Fluorogenic Substrate Chemical Structure
  45. GC48995 Enteropeptidase Fluorogenic Substrate (trifluoroacetate salt) A fluorogenic substrate of enteropeptidase Enteropeptidase Fluorogenic Substrate (trifluoroacetate salt) Chemical Structure
  46. GC49322 GGACK (hydrochloride) A uPA and factor Xa inhibitor GGACK (hydrochloride) Chemical Structure
  47. GC49437 Gliotoxin-13C13 An internal standard for the quantification of gliotoxin Gliotoxin-13C13 Chemical Structure
  48. GC45668 Gly-Arg-AMC (hydrochloride) A fluorogenic substrate for cathepsin C Gly-Arg-AMC (hydrochloride) Chemical Structure
  49. GA22303 H-D-Pro-Phe-Arg-pNA . 2 HCl pFR-pNA, chromogenic substrate for the determination of plasma kallikrein-like activity. CAS Number (net): 64816-19-9. H-D-Pro-Phe-Arg-pNA . 2 HCl Chemical Structure
  50. GC45471 H-Gly-Arg-pNA (hydrochloride)   H-Gly-Arg-pNA (hydrochloride) Chemical Structure
  51. GC49605 H-Gly-Pro-Hyp-OH (acetate) A peptide DPP-4 inhibitor H-Gly-Pro-Hyp-OH (acetate) Chemical Structure
  52. GC49915 Hexa-D-Arginine (trifluoroacetate salt) A furin inhibitor Hexa-D-Arginine (trifluoroacetate salt) Chemical Structure
  53. GC45639 Hexapeptide-11 (acetate) A synthetic hexapeptide Hexapeptide-11 (acetate) Chemical Structure
  54. GC48387 Inostamycin A A bacterial metabolite with anticancer activity Inostamycin A Chemical Structure
  55. GC52472 Inostamycin A (sodium salt) A bacterial metabolite with anticancer activity Inostamycin A (sodium salt) Chemical Structure
  56. GC49142 Isorhoifolin Isorhoifolin ist ein Flavonoidglykosid aus Periploca nigrescens-BlÄttern. Isorhoifolin Chemical Structure
  57. GC43922 Isovaleryl-L-carnitine (chloride) Isovaleryl-L-Carnitin (Chlorid), ein Produkt des Katabolismus von L-Leucin, ist ein starker Aktivator der Ca2+--abhÄngigen Proteinase (Calpain) menschlicher Neutrophiler. Isovaleryl-L-carnitine (chloride) Chemical Structure
  58. GC18699 JCP174 JCP174 ist ein Inhibitor der Palmitoyl-Protein-Thioesterase-1 (TgPPT1), einer Depalmitoylase im Parasiten T. JCP174 Chemical Structure
  59. GC49547 L-Glutamic Acid γ-p-Nitroanilide (hydrate) A colorimetric substrate for γ-glutamyl transpeptidase L-Glutamic Acid γ-p-Nitroanilide (hydrate) Chemical Structure
  60. GC49205 L-Leu-AMC (hydrochloride) L-Leucin-7-amido-4-methylcumarin (Leu-AMC)-Hydrochlorid ist ein hellblaues fluorogenes Peptidylsubstrat fÜr LAP3 (Leucin-Aminopeptidase). L-Leu-AMC (hydrochloride) Chemical Structure
  61. GC49751 Lefamulin Lefamulin (BC-3781) ist ein oral wirksames Antibiotikum. Lefamulin Chemical Structure
  62. GC18363 Mca-DEVDAPK(Dnp)-OH Mca-DEVDAPK(Dnp)-OH ist ein fluorogenes Substrat fÜr Caspase-3. Mca-DEVDAPK(Dnp)-OH Chemical Structure
  63. GC44132 Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2 Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2 ist ein fluorogenes Substrat fÜr die Matrix-Metalloproteinase-14 (MMP-14). Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2 Chemical Structure
  64. GC44235 MMP Inhibitor I (trifluoroacetate salt) MMP inhibitor I is a peptide inhibitor of matrix metalloproteinase-1 (MMP-1), MMP-2, and MMP-3 (IC50s = 1.3, 30, and 150 μM, respectively). MMP Inhibitor I (trifluoroacetate salt) Chemical Structure
  65. GC18218 MMP-3 Inhibitor

    MMP-3 inhibitor is a peptide inhibitor of matrix metalloproteinase-3 (MMP-3) with a Ki value of 95 nM.

     MMP-3 Inhibitor Chemical Structure
  66. GC40624 MMP-3 Inhibitor VIII Matrix metalloproteinases (MMPs) belong to a family of proteases that play a crucial role in tissue remodeling and repair by degrading extracellular matrix proteins to enable cell migration. MMP-3 Inhibitor VIII Chemical Structure
  67. GC18616 MMP-8 Inhibitor I MMP-8 Inhibitor I is a selective inhibitor of the neutrophil collagenase matrix metalloproteinase-8 (MMP-8) with an IC50 value of 4 nM. MMP-8 Inhibitor I Chemical Structure
  68. GC45515 MX1013 MX1013 ist ein potenter, irreversibler Dipeptid-Caspase-Inhibitor mit antiapoptotischer AktivitÄt. MX1013 hemmt die rekombinante menschliche Caspase 3 mit einem IC50 von 30 nM. MX1013 Chemical Structure
  69. GC45667 N-(p-Tosyl)-GPR-pNA (acetate) A colorimetric thrombin substrate N-(p-Tosyl)-GPR-pNA (acetate) Chemical Structure
  70. GC47806 N-p-Tosyl-Gly-Pro-Lys-pNA (acetate) A colorimetric plasmin substrate N-p-Tosyl-Gly-Pro-Lys-pNA (acetate) Chemical Structure
  71. GC44313 Naphthofluorescein Naphthofluorescein hemmt die Wechselwirkung zwischen HIF-1 und Mint3.Naphthofluorescein unterdrÜckt die Mint3-abhÄngige HIF-1-AktivitÄt und Glykolyse in Krebszellen und Makrophagen ohne ZytotoxizitÄt in vitro und nachteilige Wirkung in vivo. Naphthofluorescein ist auch eine fluoreszierende pH-empfindliche Sonde, die fÜr die funktionelle Cerenkov-Bildgebung verwendet werden kann. Naphthofluorescein Chemical Structure
  72. GC49186 O-Demethyl Apremilast An active metabolite of apremilast O-Demethyl Apremilast Chemical Structure
  73. GC40256 p-APMSF (hydrochloride) p-APMSF is an irreversible inhibitor of serine proteases with Ki values of 1.02, 1.18, 1.5, and 1.54 μM for bovine trypsin, human thrombin, bovine plasmin, and bovine Factor Xa, respectively. p-APMSF (hydrochloride) Chemical Structure
  74. GC49024 Palmitic Acid MaxSpec® Standard A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Palmitic Acid MaxSpec® Standard Chemical Structure
  75. GC49023 Palmitic Acid-d9 MaxSpec® Standard A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Palmitic Acid-d9 MaxSpec® Standard Chemical Structure
  76. GC49702 Papain Inhibitor (trifluoroacetate salt) A peptide inhibitor of papain Papain Inhibitor (trifluoroacetate salt) Chemical Structure
  77. GC40622 Penicillide Penicillid (Vermixocin A), isoliert aus auf Reis kultiviertem Talaromyces derxii, zeigt eine hemmende AktivitÄt gegen Acyl-CoA:Cholesterin-Acyltransferase (ACAT). Penicillide Chemical Structure
  78. GC40265 Pheleuin Pheleuin is a pyrazinone derivative synthesized from a dipeptide aldehyde. Pheleuin Chemical Structure
  79. GC46019 Pluviatolide Pluviatolid ((-)-Pluviatolid) ist ein Lignan, das in der Rinde von Zanthoxylum pluviatile Hartley vorkommt. Pluviatolide Chemical Structure
  80. GC49108 Racecadotril-d5 An internal standard for the quantification of racecadotril Racecadotril-d5 Chemical Structure
  81. GC48101 SSAA09E1 A SARS-CoV entry inhibitor SSAA09E1 Chemical Structure
  82. GC18565 Suc-AAP-Abu-pNA Suc-AAP-Abu-pNA is a chromogenic peptide substrate for pancreatic elastase. Suc-AAP-Abu-pNA Chemical Structure
  83. GC52447 Suc-Leu-Leu-Val-Tyr-AMC (trifluoroacetate salt) A fluorogenic substrate for the 20S proteasome and calpains Suc-Leu-Leu-Val-Tyr-AMC (trifluoroacetate salt) Chemical Structure
  84. GC44963 Suc-Leu-Tyr-AMC The calpains are a family of calcium-dependent cysteine proteases, with calpain I (μ-calpain) requiring micromolar calcium and calpain II (m-calpain) requiring millimolar calcium. Suc-Leu-Tyr-AMC Chemical Structure
  85. GA23570 Suc-Tyr-Val-Ala-Asp-pNA Suc-YVAD-pNA, a chromogenic caspase-1 substrate. Suc-Tyr-Val-Ala-Asp-pNA Chemical Structure
  86. GC44967 Suc-YVAD-AMC (acetate) Suc-YVAD-AMC is a fluorogenic substrate for caspase-1. Suc-YVAD-AMC (acetate) Chemical Structure
  87. GC48764 Sydowinin B A xanthone polyketide with immunosuppressant activity Sydowinin B Chemical Structure
  88. GC48174 Thiorphan-d5 An internal standard for the quantification of thiorphan Thiorphan-d5 Chemical Structure
  89. GC45066 Tosyl Phenylalanyl Chloromethyl Ketone Tosyl-Phenylalanyl-Chloromethyl-Keton (L-1-Tosylamido-2-Phenylethyl-Chloromethyl-Keton; L-Tosyl-Phenylalanyl-Chloromethyl-Keton) ist ein potenter Serinprotease-Inhibitor, der mit dem Retinoblastoma-Protein (RB)-bindenden Kern des HPV-18-E7-Proteins reagiert und abschafft seine RB-BindungsfÄhigkeit. Tosyl Phenylalanyl Chloromethyl Ketone Chemical Structure
  90. GC49685 Trifluoroacetyl Tripeptide-2 (acetate) A peptide inhibitor of pancreatic and neutrophil elastases Trifluoroacetyl Tripeptide-2 (acetate) Chemical Structure
  91. GC45086 Trigalacturonic Acid

    Trigalacturonic acid is an oligosaccharide that inhibits proteinase activity in tomato plants (ED50 = 2.6 μg/plant).

     Trigalacturonic Acid Chemical Structure
  92. GC49835 Tumulosic Acid TumulosinsÄure, ein Triterpenoid, hemmt die KLK5-ProteaseaktivitÄt (IC50 = 14,84 μ M). Tumulosic Acid Chemical Structure
  93. GC48471 Z-(L-Arg)-AMC (hydrochloride) Z-(L-Arg)-AMC (Hydrochlorid) ist ein fluorogenes Substrat fÜr Trypsin und Papain. Z-(L-Arg)-AMC (hydrochloride) Chemical Structure
  94. GC45177 Z-AEVD-FMK

    Z-AEVD-FMK is an irreversible inhibitor of caspase-10 and related caspases.

     Z-AEVD-FMK Chemical Structure
  95. GA23742 Z-D-Arg-Gly-Arg-pNA . 2 HCl Z-RGR-pNA is a chromogenic substrate for the determination of factor Xa. Z-D-Arg-Gly-Arg-pNA . 2 HCl Chemical Structure
  96. GC13859 Z-DEVD-AFC Z-DEVD-AFC ist ein zellgÄngiges Substrat fÜr Caspase-3, das bei Spaltung des AFC-Fluorophors eine Fluoreszenzverschiebung verursacht. Z-DEVD-AFC kann verwendet werden, um die AktivitÄt von Caspase-3-Ähnlichen Enzymen nachzuweisen. Z-DEVD-AFC Chemical Structure
  97. GC49145 Z-FR-AMC (trifluoroacetate salt) A fluorogenic substrate for cathepsin L Z-FR-AMC (trifluoroacetate salt) Chemical Structure
  98. GC45181 Z-IETD-AFC Z-IETD-AFC, ein spezifisches Fluoreszenzsubstrat, kann verwendet werden, um die katalytische AktivitÄt von Caspase-8 zu bestimmen. Z-IETD-AFC Chemical Structure
  99. GC40151 Z-VAD-AMC (acetate) Z-VAD-AMC is a fluorogenic substrate for caspase-1. Z-VAD-AMC (acetate) Chemical Structure

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