CRTH2
CRTh2 (chemoattractant receptor homologous molecule expressed on T-Helper type 2 cells ) is a G-protein coupled receptor for prostaglandin D2. Activation of CRTh2 increases the chemotaxis of Th2 cells/eosinophils/basophil, as well as eosinophil degranulation and Th2 cells cytokine release.
Produkte für CRTH2
- Bestell-Nr. Artikelname Informationen
- GC12434 AZD1981 AZD1981 ist ein potenter und selektiver CRTh2-Antagonist; verdrÄngt radioaktiv markiertes PGD2 von humanem rekombinantem DP2 mit hoher Potenz (pIC50 = 8,4).
- GC13196 NVP-QAV680 potent and selective CRTh2 receptor antagonist