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Startseite >> Signaling Pathways >> Obesity, Appetite Control & Diabetes

Obesity, Appetite Control & Diabetes

Obesity, Appetite Control & Diabetes

Satiety, appetite, and craving are CNS drives, whereas metabolism and energy utilization are peripheral endocrine actions.
Stephen M. Stahl, M.D., Ph.D. read more

Ziele für  Obesity, Appetite Control & Diabetes

Produkte für  Obesity, Appetite Control & Diabetes

  1. Bestell-Nr. Artikelname Informationen
  2. GC49008 α-Muricholic Acid-d4 An internal standard for the quantification of α-muricholic acid α-Muricholic Acid-d4 Chemical Structure
  3. GC40105 βARK1 Inhibitor βARK1-Inhibitor (Methyl-5-[2-(5-nitro-2-furyl)vinyl]-2-furoat) ist ein GRK2 (β-ARK1)-Inhibitor. βARK1 Inhibitor Chemical Structure
  4. GC46314 (±)-β-Hydroxybutyrate-d4 (sodium salt) An internal standard for the quantification of (±)βhydroxybutyrate (±)-β-Hydroxybutyrate-d4 (sodium salt) Chemical Structure
  5. GC45618 (±)-trans-GK563 A GVIA iPLA2 inhibitor (±)-trans-GK563 Chemical Structure
  6. GC40270 (±)5(6)-DiHET

    5(6)-DiHET is a fully racemic version of the enantiomeric forms biosynthesized from 5(6)-EET by epoxide hydrolases.

     (±)5(6)-DiHET Chemical Structure
  7. GC45252 (-)-Sitagliptin Carbamoyl Glucuronide (-)-Sitagliptin carbamoyl glucuronide is a minor phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin. (-)-Sitagliptin Carbamoyl Glucuronide Chemical Structure
  8. GC49066 (R)-Hydroxychloroquine (sulfate) An isomer of hydroxychloroquine (R)-Hydroxychloroquine (sulfate) Chemical Structure
  9. GC49067 (S)-Hydroxychloroquine (sulfate) An isomer of hydroxychloroquine (S)-Hydroxychloroquine (sulfate) Chemical Structure
  10. GC46365 1,1'-(Azodicarbonyl)dipiperidine A Mitsunobu reagent 1,1'-(Azodicarbonyl)dipiperidine Chemical Structure
  11. GC41777 1,2,3-Tripalmitoleoyl-rac-glycerol 1,2,3-Tripalmitoleoyl-rac-glycerol is a triacylglycerol that contains palmitoleic acid at the sn-1, sn-2, and sn-3 positions. 1,2,3-Tripalmitoleoyl-rac-glycerol Chemical Structure
  12. GC45747 1,2,3-Tripalmitoyl-d31-rac-glycerol An internal standard for the quantification of 1,2,3-tripalmitoyl glycerol 1,2,3-Tripalmitoyl-d31-rac-glycerol Chemical Structure
  13. GC41794 1,2-Diheptanoyl-sn-glycero-3-PC 1,2-Diheptanoyl-sn-glycero-3-PC (DHPC-C7) is a synthetic phosphatidylcholine containing the short-chain (7:0) heptanoic acid at the sn-1 and sn-2 positions. 1,2-Diheptanoyl-sn-glycero-3-PC Chemical Structure
  14. GC46477 1-Amino-1-deoxy-D-fructose (hydrochloride) An amino monosaccharide 1-Amino-1-deoxy-D-fructose (hydrochloride) Chemical Structure
  15. GC42035 1-Palmitoyl-2-Stearoyl-3-Oleoyl-rac-glycerol 1-Palmitoyl-2-stearoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains palmitic, stearic, and oleic acid at the sn-1, sn-2, and sn-3 positions, respectively. 1-Palmitoyl-2-Stearoyl-3-Oleoyl-rac-glycerol Chemical Structure
  16. GC46052 1-Pentadecanoyl-rac-glycerol A monoacylglycerol 1-Pentadecanoyl-rac-glycerol Chemical Structure
  17. GC45320 1-Stearoyl-3-Oleoyl-rac-glycerol   1-Stearoyl-3-Oleoyl-rac-glycerol Chemical Structure
  18. GC46400 10(11)-Cl-BBQ Mixture A mixture that acts as an AhR agonist 10(11)-Cl-BBQ Mixture Chemical Structure
  19. GC40317 10(R)-PAHSA 10(R)-PAHSA is a stereoisomer of 10-PAHSA, an endogenous lipid that belongs to a collection of branched fatty acid esters of hydroxy fatty acids (FAHFAs). 10(R)-PAHSA Chemical Structure
  20. GC40318 10(S)-PAHSA 10(S)-PAHSA is a stereoisomer of 10-PAHSA, an endogenous lipid that belongs to a collection of branched fatty acid esters of hydroxy fatty acids (FAHFAs). 10(S)-PAHSA Chemical Structure
  21. GC52071 10-oxo-12(Z)-Octadecenoic Acid A metabolite of linoleic acid and an activator of TRPV1 10-oxo-12(Z)-Octadecenoic Acid Chemical Structure
  22. GC52398 10-oxo-12(Z)-Octadecenoic Acid ethyl ester An ester form of 10-oxo-12(Z)-octadecenoic acid 10-oxo-12(Z)-Octadecenoic Acid ethyl ester Chemical Structure
  23. GC52428 10-oxo-12(Z)-Octadecenoic Acid-d5 An internal standard for the quantification of 10-oxo-12(Z)-octadecenoic acid 10-oxo-12(Z)-Octadecenoic Acid-d5 Chemical Structure
  24. GC41873 10-Thiastearic Acid Heteroatom-substituted fatty acids have been observed to modulate the extension and desaturating of fatty acids, and to influence their distribution within phospholipids pools. 10-Thiastearic Acid Chemical Structure
  25. GC48710 11-Dehydrocorticosterone 11-Dehydrocorticosteron ist ein kÖrpereigenes Corticosteroid. 11-Dehydrocorticosterone Chemical Structure
  26. GC40320 12-PAHSA Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity. 12-PAHSA Chemical Structure
  27. GC18783 13,14-dihydro-15-keto Prostaglandin E1 13,14-dihydro-15-keto Prostaglandin E1 (PGE1) is a metabolite of PGE1 with much reduced biological activity. 13,14-dihydro-15-keto Prostaglandin E1 Chemical Structure
  28. GC41907 13C C16 Sphingomyelin (d18:1/16:0) 13C C16 Sphingomyelin is an isotopically enriched form of C16 sphingomyelin with carbon-13 occurring on the fatty acid portion. 13C C16 Sphingomyelin (d18:1/16:0) Chemical Structure
  29. GC18635 18-hydroxy-11-deoxy Corticosterone 18-hydroxy-11-deoxy Corticosterone (18-OH-DOC) is a mineralocorticoid secreted by the zona fasciculata of the adrenal gland. 18-hydroxy-11-deoxy Corticosterone Chemical Structure
  30. GC49671 2,3-Oxidosqualene An intermediate in the biosynthesis of sterols 2,3-Oxidosqualene Chemical Structure
  31. GC10289 2-NBDG

    2-NBDG ist ein fluoreszenzmarkiertes 2-Deoxyglukose-Analogon, das als Tracer zur Bewertung des zellulären Glukosestoffwechsels nützlich ist (Ex/Em: 475/550 nm).

     2-NBDG Chemical Structure
  32. GC18270 22(S)-hydroxy Cholesterol A synthetic oxysterol and LXR modulator 22(S)-hydroxy Cholesterol Chemical Structure
  33. GC49169 3,8’-Biapigenin 3,8’-Biapigenin ist ein Biflavon in Hypericum perforatum L. 3,8’-Biapigenin Chemical Structure
  34. GC49850 3-Epideoxycholic Acid A secondary bile acid and an epimer of deoxycholic acid 3-Epideoxycholic Acid Chemical Structure
  35. GC18403 3-hydroxy Hexanoic Acid 3-hydroxy Hexanoic acid is a hydroxylated fatty acid that has been found in methyl-branched poly(3-hydroxyalkanoate) (PHA) polymers produced by P. 3-hydroxy Hexanoic Acid Chemical Structure
  36. GC42291 3-Hydroxyisobutyrate (sodium salt)

    3-Hydroxyisobutyrate (3-HIB) is an intermediate in the metabolism of the branched-chain amino acid valine that is secreted by skeletal muscle.

     3-Hydroxyisobutyrate (sodium salt) Chemical Structure
  37. GC42411 4-hydroxy Nonenal Alkyne

    4-hydroxy Nonenal (4-HNE) is a major aldehyde produced during the lipid peroxidation of ω-6 polyunsaturated fatty acids, such as arachidonic acid and linoleic acid.

     4-hydroxy Nonenal Alkyne Chemical Structure
  38. GC42434 4-methyl-2-Oxovalerate (sodium salt) 4-methyl-2-Oxovalerate is an immediate precursor and metabolite of L-leucine. 4-methyl-2-Oxovalerate (sodium salt) Chemical Structure
  39. GC49176 5β-Tetrahydrocortisol An endogenous metabolite of cortisol 5β-Tetrahydrocortisol Chemical Structure
  40. GC18870 6-NBDG 6-NBDG ist ein fluoreszierendes Glucose-Analogon, es kann zur Fluoreszenzbildgebung und Überwachung des Glucosetransports und -aufnahme verwendet werden. 6-NBDG Chemical Structure
  41. GC42620 8-Aminopyrene-1,3,6-trisulfonic Acid (sodium salt) 8-Aminopyrene-1,3,6-trisulfonic Acid (Natriumsalz) ist ein wasserlÖslicher anionischer Fluoreszenzfarbstoff. 8-Aminopyrene-1,3,6-trisulfonic Acid (sodium salt) Chemical Structure
  42. GC40323 9(R)-PAHSA 9(R)-PAHSA is a stereoisomer of 9-PAHSA, an endogenous lipid that belongs to a collection of branched fatty acid esters of hydroxy fatty acids (FAHFAs). 9(R)-PAHSA Chemical Structure
  43. GC40324 9(S)-PAHSA 9-PAHSA is a newly identified endogenous lipid that belongs to a collection of branched fatty acid esters of hydroxy fatty acids (FAHFAs). 9(S)-PAHSA Chemical Structure
  44. GC46757 9(Z),11(E)-Conjugated Linoleic Acid (sodium salt) An isomer of linoleic acid 9(Z),11(E)-Conjugated Linoleic Acid (sodium salt) Chemical Structure
  45. GC40325 9-PAHSA Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity. 9-PAHSA Chemical Structure
  46. GP10060 a-MSH, amide

    a-MSH (α-Melanocortin-stimulierendes Hormon), Amid aktiviert den Melanocortin-1-Rezeptor und aktiviert das zyklische AMP (cAMP) Signal über einen G-Protein-Transporter, kann Melanin synthetisieren.

     a-MSH, amide Chemical Structure
  47. GC42674 ABD459 ABD459 is a neutral antagonist of the central cannabinoid 1 (CB1) receptor (Ki = 8.6 nM). ABD459 Chemical Structure
  48. GC49406 ACT-373898 ACT-373898 ist ein inaktiver CarbonsÄuremetabolit von Macitentan. ACT-373898 Chemical Structure
  49. GC49231 Adenylosuccinic Acid (ammonium salt) A purine nucleotide and an intermediate in the purine nucleotide cycle Adenylosuccinic Acid (ammonium salt) Chemical Structure
  50. GP10076 Agouti-related Protein (AGRP) (25-82), human Agouti-related Protein (AGRP) (25-82), human Chemical Structure
  51. GC49110 AICA Ribonucleotide An AMPK activator AICA Ribonucleotide Chemical Structure
  52. GC46821 Ajoene Ajoene, eine aus Knoblauch gewonnene Verbindung, ist ein antithrombotisches und antimykotisches Mittel. Ajoene Chemical Structure
  53. GC40812 all-cis-4,7,10,13,16-Docosapentaenoic Acid Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oils. all-cis-4,7,10,13,16-Docosapentaenoic Acid Chemical Structure
  54. GC40289 all-cis-4,7,10,13,16-Docosapentaenoic Acid methyl ester all-cis-4,7,10,13,16-Docosapentaenoic acid (all-cis-4,7,10,13,16-DPA) methyl ester is a more lipid-soluble form of the free acid. all-cis-4,7,10,13,16-Docosapentaenoic Acid methyl ester Chemical Structure
  55. GC49393 all-trans-13,14-Dihydroretinol A metabolite of all-trans retinoic acid all-trans-13,14-Dihydroretinol Chemical Structure
  56. GC45379 Alloxan (hydrate)   Alloxan (hydrate) Chemical Structure
  57. GC40024 Altenusin Altenusin zeigt ausgeprÄgte DPPH-RadikalfÄngeraktivitÄten. Altenusin Chemical Structure
  58. GC42786 Aminoacetone (hydrochloride) Aminoacetone is a threonine and glycine catabolite that can be converted to methylglyoxal by amine oxidases. Aminoacetone (hydrochloride) Chemical Structure
  59. GC40636 Amorfrutin A Amorfrutin A is an isoprenoid-substituted benzoic acid natural product found in the fruit of A. Amorfrutin A Chemical Structure
  60. GC42791 Amorfrutin B Amorfrutin B is a partial agonist of the peroxisome proliferator-activated receptor γ (PPARγ; Ki = 19 nM and EC50 = 73 nM) that was first isolated from A. Amorfrutin B Chemical Structure
  61. GC41406 AMP-Deoxynojirimycin The lipid messenger ceramide is converted to glucosylceramide by glucosylceramide synthase (GCS). AMP-Deoxynojirimycin Chemical Structure
  62. GC42796 Amylin (human) (trifluoroacetate salt) Amylin is a 37-residue peptide hormone secreted from pancreatic β-cells that reduces food intake, decreases glucagon secretion, slows gastric emptying, and increases satiety. Amylin (human) (trifluoroacetate salt) Chemical Structure
  63. GC42805 AN-7 α-Lipoic acid is a cyclic disulfide antioxidant that interconverts with its reduced dithiol form. AN-7 Chemical Structure
  64. GC52128 AOD-9604 AOD-9604 Chemical Structure
  65. GC52380 AOD-9604 (acetate) A synthetic lipolytic peptide AOD-9604 (acetate) Chemical Structure
  66. GC46892 ATRA-BA Hybrid A prodrug form of all-trans retinoic acid and butyric acid ATRA-BA Hybrid Chemical Structure
  67. GC49646 Aurothioglucose (hydrate) A TrxR inhibitor Aurothioglucose (hydrate) Chemical Structure
  68. GC52476 Bax Inhibitor Peptide V5 (trifluoroacetate salt) A Bax inhibitor Bax Inhibitor Peptide V5 (trifluoroacetate salt) Chemical Structure
  69. GC40889 Benzomalvin A Benzomalvin A ist ein potenter Antagonist des Neurokinin-Rezeptors, isoliert aus Penicillium sp. Benzomalvin A Chemical Structure
  70. GC18718 bpV(pic) (potassium hydrate) bpV(pic) is a bisperoxovanadium (bpV) compound that inhibits several different protein tyrosine phosphatases (PTPs), with selectivity for PTEN (IC50 = 31 nM). bpV(pic) (potassium hydrate) Chemical Structure
  71. GC46104 Butyric Acid-d7 An internal standard for the quantification of sodium butyrate Butyric Acid-d7 Chemical Structure
  72. GC43022 C14 Ceramide (d18:1/14:0)

    C14 Ceramide is an endogenous ceramide generated by ceramide synthase 6.

     C14 Ceramide (d18:1/14:0) Chemical Structure
  73. GC43033 C16 Lactosylceramide (d18:1/16:0) C16 Lactosylceramide is an endogenous bioactive sphingolipid. C16 Lactosylceramide (d18:1/16:0) Chemical Structure
  74. GC43035 C16 Sphingomyelin (d18:1/16:0) Sphingomyelins are complex membrane lipids composed of phosphorylcholine, sphingosine, and an acylated group, such as a fatty acid. C16 Sphingomyelin (d18:1/16:0) Chemical Structure
  75. GC43047 C18 Ceramide (d18:1/18:0)

    C18 Ceramide is an endogenous bioactive sphingolipid.

     C18 Ceramide (d18:1/18:0) Chemical Structure
  76. GC46987 C18 Ceramide-d3 (d18:1/18:0-d3) An internal standard for the quantification of C18 ceramide C18 Ceramide-d3 (d18:1/18:0-d3) Chemical Structure
  77. GC46988 C18 Ceramide-d7 (d18:1-d7/18:0) An internal standard for the quantification of C18 ceramide C18 Ceramide-d7 (d18:1-d7/18:0) Chemical Structure
  78. GC43048 C18 dihydro Ceramide (d18:0/18:0)

    A bioactive sphingolipid

     C18 dihydro Ceramide (d18:0/18:0) Chemical Structure
  79. GC43055 C18:1 Ceramide (d18:1/18:1(9Z))

    C18:1 Ceramide is a naturally occurring ceramide.

     C18:1 Ceramide (d18:1/18:1(9Z)) Chemical Structure
  80. GC43068 C20 Sphingomyelin (d18:1/20:0) C20 Sphingomyelin is a naturally occurring sphingolipid. C20 Sphingomyelin (d18:1/20:0) Chemical Structure
  81. GC43075 C24 dihydro Ceramide (d18:0/24:0)

    C24 dihydro Ceramide is a sphingolipid that has been found in the stratum corneum of human skin.

     C24 dihydro Ceramide (d18:0/24:0) Chemical Structure
  82. GC43113 Caerulein (acetate) Caerulein is an oligopeptide originally isolated from skin extracts of H. Caerulein (acetate) Chemical Structure
  83. GC49433 Capsiate Capsiat, als ein Capsaicin-Analogon, das aus einer nicht scharfen Sorte von CH-19-SÜßpaprika extrahiert wird, ist ein oral aktiver Agonist von TRPV1. Capsiate Chemical Structure
  84. GC43140 Captopril Disulfide Captoprildisulfid ist ein Metabolit von Captopril mit blutdrucksenkender Wirkung. Captopril Disulfide Chemical Structure
  85. GC40384 CAY10410 CAY10410 is an analog of prostaglandin D2/prostaglandin J2 (PGD2/PGJ2) with structural modifications intended to give it PPARγ ligand activity and resistance to metabolism. CAY10410 Chemical Structure
  86. GC41601 CAY10591 CAY10591 ist ein starker Aktivator von Sirt1 und unterdrÜckt TNF-α dosisabhÄngig. CAY10591 Chemical Structure
  87. GC43180 CAY10592 Peroxisome proliferator-activated receptors (PPARs) α, δ, γ are ligand-activated nuclear transcription factors involved in the regulation of energy homeostasis as well as insulin sensitivity and glucose metabolism. CAY10592 Chemical Structure
  88. GC43215 CCK Octapeptide (non-sulfated), (trifluoroacetate salt) Cholecystokinin (CCK) octapeptide is a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety. CCK Octapeptide (non-sulfated), (trifluoroacetate salt) Chemical Structure
  89. GC40203 Cholesterol-d6

    Cholesterol-d6 is intended for use as an internal standard for the quantification of cholesterol by GC- or LC-MS.

     Cholesterol-d6 Chemical Structure
  90. GC47085 Cholesterol-d7 An internal standard for the quantification of cholesterol Cholesterol-d7 Chemical Structure
  91. GC49146 Colupulone A β-acid with diverse biological activities Colupulone Chemical Structure
  92. GC49868 D-α-Tocopheryl Quinone An oxidative metabolite of vitamin E D-α-Tocopheryl Quinone Chemical Structure
  93. GC47204 D-Fructose-13C6 An internal standard for the quantification of D-fructose D-Fructose-13C6 Chemical Structure
  94. GC43376 Dapagliflozin-3-O-β-D-Glucuronide

    Dapagliflozin-3-O-β-D-glucuronide is a metabolite of dapagliflozin.

     Dapagliflozin-3-O-β-D-Glucuronide Chemical Structure
  95. GC47171 Dapagliflozin-d5 Dapagliflozin D5 (BMS-512148 D5) ist ein mit Deuterium gekennzeichnetes Dapagliflozin. Dapagliflozin-d5 Chemical Structure
  96. GA21369 Deamino-histidine A metabolite of histidine Deamino-histidine Chemical Structure
  97. GC43408 Deoxycholic Acid (sodium salt hydrate) DesoxycholsÄure (CholansÄure) Natriumhydrat, eine GallensÄure, ist ein Nebenprodukt des Darmstoffwechsels, das den G-Protein-gekoppelten GallensÄurerezeptor TGR5 aktiviert. Deoxycholic Acid (sodium salt hydrate) Chemical Structure
  98. GC47187 Deoxycholic Acid-d4 DesoxycholsÄure-d4 ist die mit Deuterium bezeichnete DesoxycholsÄure. Deoxycholic Acid-d4 Chemical Structure
  99. GP10126 Diazepam-Binding Inhibitor Fragment, human Diazepam-Binding Inhibitor (DBI) Fragment is encoded by the DBI gene in human. Diazepam-Binding Inhibitor Fragment, human Chemical Structure
  100. GC40666 Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate (DDC) inhibits heme production by inhibiting ferrochelatase, the enzyme that catalyzes the addition of Fe2+ to protoporphyrin IX to create heme B. Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate Chemical Structure
  101. GC49590 Docosahexaenoic Acid 1,2,3,4-13C An internal standard for the quantification of DHA Docosahexaenoic Acid 1,2,3,4-13C Chemical Structure

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