Proteases
Proteases is a general term for a class of enzymes that hydrolyze protein peptide chains. According to the way they degrade polypeptides, they are divided into two categories: endopeptidases and telopeptidases. The former can cut the large molecular weight polypeptide chain from the middle to form prions and peptones with smaller molecular weights; the latter can be divided into carboxypeptidase and aminopeptidase, which respectively remove the peptide from the free carboxyl terminus or free amino terminus of the polypeptide one by one. Chain hydrolysis produces amino acids.
A general term for a class of enzymes that hydrolyze peptide bonds in proteins. According to the way they hydrolyze polypeptides, they can be divided into endopeptidases and exopeptidases. Endopeptidase cleaves the interior of the protein molecule to form smaller molecular weight peptones and peptones. Exopeptidase hydrolyzes peptide bonds one by one from the end of the free amino group or carboxyl group of protein molecules, and frees amino acids, the former is aminopeptidase and the latter is carboxypeptidase. Proteases can be classified into serine proteases, sulfhydryl proteases, metalloproteases and aspartic proteases according to their active centers and optimum pH. According to the optimum pH value of its reaction, it is divided into acidic protease, neutral protease and alkaline protease. The proteases used in industrial production are mainly endopeptidases.
Proteases are widely found in animal offal, plant stems and leaves, fruits and microorganisms. Microbial proteases are mainly produced by molds and bacteria, followed by yeast and actinomycetes.
Enzymes that catalyze the hydrolysis of proteins. There are many kinds, the important ones are pepsin, trypsin, cathepsin, papain and subtilisin. Proteases have strict selectivity for the reaction substrates they act on. A protease can only act on certain peptide bonds in protein molecules, such as the peptide bonds formed by the hydrolysis of basic amino acids catalyzed by trypsin. Proteases are widely distributed, mainly in the digestive tract of humans and animals, and are abundant in plants and microorganisms. Due to limited animal and plant resources, the industrial production of protease preparations is mainly prepared by fermentation of microorganisms such as Bacillus subtilis and Aspergillus terrestris.
Ziele für Proteases
- Caspase(122)
- Aminopeptidase(21)
- ACE(75)
- Calpains(11)
- Carboxypeptidase(9)
- Cathepsin(80)
- DPP-4(18)
- Elastase(25)
- Gamma Secretase(46)
- HCV Protease(37)
- HSP(107)
- HIV Integrase(30)
- HIV Protease(34)
- MMP(219)
- NS3/4a protease(4)
- Serine Protease(17)
- Thrombin(50)
- Urokinase(2)
- Cysteine Protease(0)
- Other Proteases(15)
- Tyrosinases(50)
- 15-PGDH(1)
- Acetyl-CoA Carboxylase(14)
- Acyltransferase(64)
- Aldehyde Dehydrogenase (ALDH)(30)
- Aminoacyl-tRNA Synthetase(9)
- ATGL(1)
- Dipeptidyl Peptidase(49)
- Drug Metabolite(513)
- E1/E2/E3 Enzyme(92)
- Endogenous Metabolite(1764)
- FABP(31)
- Farnesyl Transferase(21)
- Glutaminase(17)
- Glutathione Peroxidase(35)
- Isocitrate Dehydrogenase (IDH)(28)
- Lactate Dehydrogenase(19)
- Lipoxygenase(274)
- Mitochondrial Metabolism(260)
- NEDD8-activating Enzyme(6)
- Neprilysin(12)
- PAI-1(14)
- Ser/Thr Protease(49)
- Tryptophan Hydroxylase(12)
- Xanthine Oxidase(18)
- MALT1(10)
- PCSK9(13)
- ADAMTS(1)
- Density Lipoprotein(0)
- TrxR(1)
- DGK(3)
Produkte für Proteases
- Bestell-Nr. Artikelname Informationen
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GC38556
1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine
1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholin ist ein kÖrpereigener Metabolit.
-
GC30641
1-Naphthol (Fourrine ERN)
1-Naphthol ist eine fluoreszierende Molekularsonde mit Protonentransfer im angeregten Zustand (ESPT).
-
GC39470
1-Octanol
1-Octanol (Octanol), ein gesÄttigter Fettalkohol, ist ein Inhibitor der T-Typ-CalciumkanÄle (T-KanÄle) mit einem IC50 von 4 μM fÜr native T-StrÖme.
-
GC74657
1-Octanol-d17
Octanol-d17
1-Octanol-d17 ist das Deuterium mit 1-Octanol markiert. -
GC40183
1-Oleoyl Glycerol
18:1-MG, MG(18:1), 1-Monoolein, 1-Oleoyl-rac-glycerol
1-Oleoylglycerol ist ein kÖrpereigener Metabolit. -
GC92061
1-Palmitoyl-2-13(S)-HODE-sn-glycero-3-PC
1-Hexadecanoyl-2-13(S)-HODE-sn-glycero-3-Phosphocholine; 13(S)-Hydroxyoctadecadienoic Acid-PLPC; 1-Palmitoyl-2-13(S)-HODE-sn-glycero-3-Phosphocholine; 1-Palmitoyl-2-(13-hydroxy-cis-9,trans-11-octadecadienoyl)-L-3-phosphatidylcholine
1-Palmitoyl-2-13(S)-HODE-sn-glycero-3-PC ist ein oxidiertes Phospholipid, das Palmitinsäure und 13S-HODE an den Positionen sn-1 und sn-2 enthält. -
GC46488
1-Palmitoyl-2-Docosahexaenoyl-sn-glycero-3-PC
1-Palmitoyl-2-Docosahexaenoyl-sn-glycero-3-Phosphocholine, 1-Palmitoyl-2-Docosahexaenoyl-sn-glycero-3-Phosphatidylcholine, PC(16:0/22:6), 16:0/22:6-PC, PDPC
A phospholipid -
GC68501
1-Palmitoyl-2-oleoyl-sn-glycerol
1-Palmitoyl-2-oleoyl-sn-glycerol ist eine endogene Metabolit und auch der Hauptdiacylglycerin in Hypoxie-induzierbaren Faktor (HIF)-1 bei Algen.
-
GC49366
1-Salicylate Glucuronide
Salicyl Phenolic Glucuronide, Salicylic Acid Phenolic Glucuronide
A metabolite of salicylic acid and aspirin -
GC42039
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC
15(S)-HETE-SAPC, 15(S)-Hydroxyeicostetraenoic Acid-SAPC, 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-Phosphatidylcholine
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position. -
GC42040
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE
15(S)-HETE-SAPE, 15(S)-Hydroxyeicosatetraenoic Acid-SAPE, 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-Phosphatidylethanolamine
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position. -
GC49730
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE-d11
15(S)-HETE-SAPE-d11, 15(S)-Hydroxyeicosatetraenoic Acid-SAPE-d11, 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-Phosphatidylethanolamine-d11
An internal standard for the quantification of 1-stearoyl-2-15(S)-HETE-sn-glycero-3-PE -
GC42041
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC
15(S)-HpETE-SAPC, 15(S)-Hydroperoxyeicostetraenoic Acid-SAPC, 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-Phosphatidylcholine
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position. -
GC42042
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-phosphoethanolamine, 15(S)-HpETE-SAPE, 15(S)-hydroperoxyeicostetraenoic acid-SAPE
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position. -
GC11139
1-Stearoyl-2-Arachidonoyl-sn-glycero-3-PC
SAPC
A phospholipid -
GC68502
1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine
1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholin kann als Modell für flüchtige Verbindungen verwendet werden, die zur Untersuchung von Phosphatidylcholin-Molekülarten eingesetzt werden. Diese Methode wurde auf tatsächliche Lebensmittelproben angewendet, nämlich Sojalecithin.
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GC40971
10(S),17(S)-DiHDHA
10(S),17(S)-DiHDoHE, PDX, Protectin DX
10(S),17(S)-DiHDHA (auch als Neuroprotectin D1 bekannt, wenn es in neuronalen Geweben produziert wird) ist eine von DHA abgeleitete DihydroxyfettsÄure, die starke schÜtzende und entzÜndungshemmende AktivitÄten aufweist. -
GC49820
10,11-dihydro-10,11-dihydroxy Carbamazepine
10,11-dihydro-10,11-dihydroxy CBZ, CBZ-diol, Dihydroxycarbazepine, Dihydroxycarbamazepine
A metabolite of carbamazepine and oxcarbazepine -
GC66057
10,11-Dihydrocarbamazepine
10,11-Dihydrocarbamazepin ist der aktive Metabolit von Oxcarbazepin. 10,11-Dihydrocarbamazepin ist ebenfalls ein Zwischenprodukt. Oxcarbazepin wird schnell und fast vollstÄndig in 10,11-Dihydrocarbazepin mit wahrscheinlicher antikonvulsiver Wirksamkeit umgewandelt.
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GC38881
10,12-Tricosadiynoic acid
10,12-TricosadiinsÄure ist ein hochspezifischer, selektiver, hochaffiner und oral aktiver Acyl-CoA-Oxidase-1 (ACOX1)-Inhibitor.
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GC49872
10-Formyltetrahydrofolate (sodium salt) (technical grade)
10-CHO-FH4, 10-CHO-THF, N10-Formyltetrahydrofolate, 10-formyl H4PteGlu, 10-fTHF
10-Formyltetrahydrofolat (Natriumsalz) (technische QualitÄt) ist eine Form von TetrahydrofolsÄure, die als Spender von Formylgruppen im Anabolismus wirkt. -
GC49118
10-hydroxy Warfarin
A metabolite of (R)-warfarin
-
GC33800
10Z-Nonadecenoic acid
Nonadeca-10(Z)-enoic Acid
10Z-NonadecensÄure ist eine Art langkettige FettsÄure mit Anti-Tumor-AktivitÄt. -
GC40368
11(R)-HEPE
11(R)-HEPE is produced by the oxidation of EPA by 11(R)-LO.
-
GC40445
11(R)-HETE
11(R)-Hydroxyeicosatetraenoic Acid
11(R)-HETE is biosynthesized by 11(R)-LOs of the sea urchin, S. -
GC39223
11-Beta-hydroxyandrostenedione
11β-Hydroxy-4-androsten-3,17-dione, NSC 12168, NSC 17102, 11OHA4, U-2826
11-Beta-Hydroxyandrostenedion (4-Androsten-11β-ol-3,17-dion) ist ein Steroid, das hauptsÄchlich in der Nebenniere vorkommt (11β-Hydroxylase ist im Nebennierengewebe vorhanden, fehlt jedoch im Eierstockgewebe). -
GC40730
11-cis Vaccenyl Acetate
11-cis Vaccenylacetat ist ein männliches spezifisches Lipid, das das Aggregationsverhalten sowohl bei männlichen als auch bei weiblichen Fliegen vermittelt, wodurch einige Dutzend olfaktorische Neuronen aktiviert werden, die sich in T1-Sensillen auf der Antenne sowohl männlicher als auch weiblicher Fliegen befinden.
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GC40394
11-deoxy Corticosterone
DOC, NSC 11319, 21-hydroxy Progesterone
11-Deoxykortikosteron ist ein Steroidhormon, das von der Nebenniere produziert wird und Mineralocorticoid-Aktivität besitzt und als Vorläufer von Aldosteron wirkt.
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GC10821
11-keto-β-Boswellic Acid
11-oxo-β-Boswellic acid,KBA
11-Keto-beta-BoswelliasÄure (11-Keto-β-BoswelliasÄure) ist eine pentazyklische TriterpensÄure des Oleogumharzes aus der Rinde des Boswellia-Serratbaums, im Volksmund bekannt als Indischer Weihrauch. Die entzÜndungshemmende Wirkung von 11-Keto-beta-BoswelliasÄure beruht hauptsÄchlich auf der Hemmung der 5-Lipoxygenase (5-LOX) und der anschließenden Leukotrien- und Kernfaktor-Kappa-B-Aktivierung (NF-&7#954;B) und der Bildung des Tumor-Nekrose-Faktors Alpha Produktion. -
GC61538
11-Oxo etiocholanolone
5β-Androstane-3α-ol-11,17-dione, 11-keto Etiocholanolone, NSC 53896
11-Oxo-Etiocholanolon (11-Ketoetiocholanolon) ist ein Metabolit von Etiocholanolon. -
GC41144
11-trans Leukotriene C4
11trans LTC4
11-trans Leukotriene C4 (11-trans LTC4) is a C-11 double bond isomer of LTC4. -
GC41147
11-trans Leukotriene D4
11trans LTD4
11-trans Leukotriene D4 (11-trans LTD4) is a C-11 double bond isomer of LTD4. -
GC41149
11-trans Leukotriene E4
11trans LTE4
11-trans-Leukotrien E4 ist ein Isomer von Leukotrien E4 (LTE4). -
GC63796
116-9e
MAL2-11B
116-9e (MAL2-11B) ist ein Hsp70-Co-Chaperon-DNAJA1-Inhibitor. -
GC34016
11beta-Hydroxyprogesterone (11β-Hydroxyprogesterone)
21-Deoxycorticosterone, 11β-OHP, 11β-hydroxy Progesterone, NSC 15469, U-1701
11beta-Hydroxyprogesteron (11β-Hydroxyprogesteron) ist ein starker Inhibitor von 11&7#946;-Hydroxysteroiddehydrogenase; aktiviert auch den menschlichen Mineralokortikoidrezeptor in COS-7-Zellen mit einer ED50 von 10 nM. -
GC40447
12(R)-HETE
12(R)-Hydroxyeicosatetraenoic Acid
Biosynthesis of 12(R)-HETE in invertebrates is via lipoxygenation of arachidonic acid. -
GC40371
12(S)-HEPE
12(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 12-LO.
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GC40448
12(S)-HETE
12(S)-Hydroxyeicosatetraenoic Acid
12(S)-HETE is the predominant lipoxygenase product of mammalian platelets.
-
GC40449
12(S)-HETE MaxSpec® Standard
12(S)-HETE is the predominant lipoxygenase product of mammalian platelets.
-
GC40349
12(S)-HETE-19,20-alkyne
Click Tag 12(S)-HETE-19,20-alkyne, Click Tag 12(S)-Hydroxyeicosatetraenoic Acid-19,20-alkyne
12(S)-HETE is the predominant lipoxygenase product of mammalian platelets. -
GC41882
12(S)-HETrE
12(S)-HETrE is produced by 12-lipoxygenase oxidation of dihomo-γ-linolenic acid (DGLA).
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GC41095
12(S)-HpEPE
12(S)-HpEPE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 12-lipoxygenase on eicosapentaenoic acid.
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GC41122
12(S)-HpETE
12(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of platelet or leukocyte 12-lipoxygenase (12-LO) on arachidonic acid.
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GC41123
12-epi Leukotriene B4
12epi LTB4
Leukotriene B4 (LTB4) compounds are produced by both enzymatic and non-enzymatic processes. -
GC46416
12-epi Leukotriene B4-d4
12epi LTB4d4
A neuropeptide with diverse biological activities -
GC45962
12-hydroxy Lauric Acid
ω-hydroxy Lauric Acid, NSC 159293, NSC 664211
12-Hydroxy-LaurinsÄure ist ein kÖrpereigener Metabolit. -
GC60443
12-Ketodeoxycholic acid
12-keto LCA, 12-keto Lithocholate, 12-KLCA, 12-oxo LCA, 12-oxo Lithocholate, 12-oxo Lithocholic Acid
12-KetodesoxycholsÄure ist eine GallensÄure, Metabolit aus der Niere. -
GC41096
12-oxo Leukotriene B4
12keto LTB4, 12oxo LTB4
Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-LO pathway. -
GC46418
12-oxo-13-HOME
An oxylipin
-
GC90652
12-oxo-9(Z)-Dodecenoic Acid
Ein Metabolit von Linolsäure und Linolensäure.
-
GC40372
12-OxoETE
12KETE
12-OxoETE is synthesized by human platelets and Aplysia nervous tissue after incubation with arachidonic acid. -
GC19462
13(R)-HODE
13(R)-HODE is the opposite enantiomer of the 13(S)-HODE produced when linoleic acid is incubated with soybean lipoxygenase.
-
GC19463
13(S)-HODE
13(S)-HODE
13(S)-HODE (13(S)-HODE), das Produkt des 15-Lipoxygenase (15-LOX)-Metabolismus von LinolsÄure, fungiert als endogener Ligand zur Aktivierung von PPARγ. -
GC41220
13(S)-HODE methyl ester
13(S)-hydroxyoctadecadienoic acid (13(S)-HODE) is a 15-lipoxygenase metabolite of linoleic acid produced in endothelial cells, leukocytes, and tumor cells.
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GC41896
13(S)-HODE-biotin
13(S)-HODE is the lipoxygenase metabolite of linoleic acid.
-
GC46420
13(S)-HODE-d4
An internal standard for the quantification of 13-HODE
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GC41897
13(S)-HOTrE
13(S)-HOTrE is the 15-lipoxygenase (15-LO) product of linolenic acid.
-
GC41898
13(S)-HOTrE(γ)
13(S)-HOTrE(γ) is the 15-LO product of γ-linolenic acid.
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GC19474
13(S)-HpODE
13(S)-HpODE is produced by the oxidation of linoleic acid by lipoxygenase-1 (LO-1) in many plants including soybean, flaxseed, apples, and tea leaves,1,2 and by 15-LO in mammals.
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GC41899
13(S)-HpOTrE
13(S)-HpOTrE is a monohydroperoxy polyunsaturated fatty acid produced in soybeans by the action of soybean LO-2 on esterified α-linolenic acid.
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GC41900
13(S)-HpOTrE(γ)
13(S)-HpOTrE(γ) is a monohydroxy PUFA produced by the action of soybean lipoxygenase-1 (LO-1) on γ-linolenic acid.
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GC62758
13-cis-Vitamin A palmitate
13-cis-Vitamin-A-Palmitat (13-cis-Retinylpalmitat) ist ein 13-cis-Isomer, das aus Vitamin-A-Palmitat in Cornflakes gebildet wird.
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GC41911
13-epi-12-oxo Phytodienoic Acid
13epi12oxo PDA
13-epi-12-oxo Phytodienoic acid (13-epi-12-oxo PDA) is a lipoxygenase metabolite of α-linolenic acid in the leaves of green plants such as corn. -
GC46436
13-OxoODE-d3
13KODEd3
A neuropeptide with diverse biological activities -
GC49759
13C17-Mycophenolic Acid
13C17-MPA
An internal standard for the quantification of mycophenolic acid -
GC41206
14(S)-HDHA
14(S)-hydroxy Docosahexaenoic Acid, 14(S)-HDoHE
14(S)-HDHA (14(S)-HDoHE) ist ein Oxygenierungsprodukt der DocosahexaensÄure (DHA). -
GC41100
14,15-dehydro Leukotriene B4
14,15dehydro LTB4
Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-lipoxygenase pathway. -
GC41145
14,15-Leukotriene C4
Eoxin C4, EXC4, 14,15LTC4
Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes. -
GC41148
14,15-Leukotriene D4
Eoxin D4, EXD4, 14,15-LTD4
14,15-Leukotriene D4 (14,15-LTD4) is a member of an alternate class of LTs synthesized by a pathway involving the dual actions of 15- and 12-lipoxygenases (15- and 12-LOs) on arachidonic acid via 15-HpETE and 14,15-LTA4 intermediates. -
GC41150
14,15-Leukotriene E4
Eoxin E4, EXE4, 14,15LTE4
Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes. -
GC41415
15(R)-Lipoxin A4
AT-Lipoxin A4
Lipid-derived lipoxins are produced at the site of vascular and mucosal inflammation where they down-regulate polymorphonuclear leukocyte recruitment and function.
-
GC40427
15(S)-HEDE
15(S)-HEDE is produced from 11Z,14Z-eicosadienoic acid by 15-LO.
-
GC40373
15(S)-HEPE
15S-hydroxy-Eicosapentaenoic Acid
15(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 15-LO. -
GC40374
15(S)-HEPE MaxSpec® Standard
15(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 15-LO.
-
GC46441
15(S)-HEPE-d5
15S-Hydroxyeicosapentaenoic Acid-d5
A neuropeptide with diverse biological activities -
GC40451
15(S)-HETE
15(S)-Hydroxyeicosatetraenoic Acid
15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. -
GC41925
15(S)-HETE Ethanolamide
15(S)-HAEA, 15(S)-Hydroxyeicosatetraenoic Acid Ethanolamide
Arachidonoyl ethanolamide was the first endogenous cannabinoid (CB) to be isolated and characterized as an agonist acting on the same receptors (CB1 and CB2) as THC. -
GC40452
15(S)-HETE MaxSpec® Standard
15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway.
-
GC40839
15(S)-HETE methyl ester
15(S)-Hydroxyeicosatetraenoic Acid methyl ester
15(S)-HETE methyl ester is a synthetic derivative of 15(S)-HETE, a major arachidonic acid metabolite from the 15-lipoxygenase pathway. -
GC41926
15(S)-HETE-biotin
15(S)-Hydroxyeicosatetraenoic Acid-biotin
15(S)-HETE is a major arachidonic acid metabolite produced by the 15-lipoxygenase pathway. -
GC46442
15(S)-HETE-d8
15(S)-Hydroxyeicosatetraenoic Acid-d8
An internal standard for the quantification of 15-HETE -
GC49894
15(S)-HETE-d8 ethyl ester
15(S)-Hydroxyeicosatetraenoic Acid-d8 ethyl ester
An internal standard for the quantification of 15(S)-HETE ethyl ester -
GC41927
15(S)-HETrE
15(S)-HETrE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of dihomo-γ-linolenic acid.
-
GC41403
15(S)-HpEDE
15(S)-HpEDE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 15-lipoxygenase on eicosadienoic acid.
-
GC41101
15(S)-HpEPE
15(S)-HpEPE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 15-lipoxygenase on eicosapentaenoic acid.
-
GC41124
15(S)-HpETE
15(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonic acid.
-
GC11988
15-acetoxy Scirpenol
4-Deacetylanguidin,NSC 267030
15-Acetoxyscirpenol, eines der Mykotoxine der Acetoxyscirpenol-Einheit (ASMs), induziert stark Apoptose und hemmt das Wachstum von Jurkat-T-Zellen dosisabhängig, indem es andere Caspasen unabhängig von Caspase-3 aktiviert. -
GC19442
15-Acetyldeoxy Nivalenol
15-Acetyl Vomitoxin, 15-AcDON, Deoxynivalenol 15-acetate, DON 15-acetate
15-Acetyldeoxy-Nivalenol ist ein hochgiftiges Trichothecen, das in Getreide vorkommt, und ein Metabolit von Deoxynivalenol, der für HepG2-Zellen toxisch ist. -
GC41937
15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide
15ketoBimatoprost, 17phenyl trinor PGF2α ethyl amide
Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide), an F-series PG analog which has been approved for use as an ocular hypotensive drug. -
GC41938
15-Lipoxygenase Inhibitor 1
15LO Inhibitor 1
15-Lipoxygenase-Inhibitor 1 ist ein selektiver Inhibitor der 15-Lipoxygenase mit einem IC50-Wert von 18 μM. 15-Lipoxygenase-Inhibitor 1 hat IC50s von 19,5 μM und 19,1 ⋼M fÜr Sojabohnen-15-Lipoxygenase (SLO) bzw. menschliche 15-Lipoxygenase-1 (15-LOX-1). 15-Lipoxygenase Inhibitor 1 hat Potenzial fÜr die Erforschung von Prostatakrebs. -
GC41940
15-OxoEDE
15KEDE
15-OxoEDE is produced by the oxidation of 15-HEDE. -
GC40376
15-OxoETE
15KETE
15-OxoETE is produced by oxidation of the 15-hydroxyl of 15-HETE. -
GC41309
16α-hydroxy Prednisolone
16α-Hydroxy-Prednisolon ist ein stereoselektiver Metabolit des 22(R)-Epimers des Glukokortikoids Budesonid Über Cytochrom P450 3A (CYP3A)-Enzyme.
-
GC35058
16-Dehydroprogesterone
16-Dehydroprogesteron ist ein steroidales Gestagen.
-
GC46451
16F16
A PDI inhibitor
-
GC45909
17α-hydroxy Pregnenolone
NSC 63853, 17-α-OH Pregnenolone
1&7#945;-Hydroxy Pregnenolon ist ein Pregnane-Steroid. -
GC71338
17β-HSD10-IN-1
17β-HSD10-IN-1 (Verbindung 9) ist ein oral aktiver Inhibitor der 17β-Hydroxysteroid Dehydrogenase Typ 10 (17β-HSD10) mit Blut-Hirn-Permeabilität.
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GC41300
17β-hydroxy Exemestane
17β-hydroxy Exemestane is the primary active metabolite of exemestane.
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GC46471
17β-hydroxy Exemestane-d3
A neuropeptide with diverse biological activities
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GC41951
17(R)-Resolvin D1
Aspirin-triggered Resolvin D1
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid and docosahexaenoic acid.