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(S)-Higenamine hydrobromide

Katalog-Nr.GC62751

(S)-Higenamin ((S)-Norcolaurin)-Hydrobromid, ein S-Enantiomer von Higenamin, ist die Einstiegsverbindung in die Benzylisochinolin-Alkaloid-Biosynthese.

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(S)-Higenamine hydrobromide Chemische Struktur

Cas No.: 105990-27-0

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

(S)-Higenamine ((S)-Norcoclaurine) hydrobromide, a S-enantiomer of Higenamine, is the entry compound in benzylisoquinoline alkaloid biosynthesis. (S)-Higenamine hydrobromide is produced by the condensation of dopamine and 4-hydroxyphenylacetaldehyde (4-HPAA) by norcoclaurine synthase (NCS)[1].

The biosynthetic pathway leading to benzylisoquinoline alkaloids originates from the enzyme-catalyzed condensation of dopamine and 4-hydrophenylacetaldehyde to yield (S)-norcoclaurine. Both substrates are secondary metabolites derived from the decarboxylation/hydroxylation/deamination of tyrosine[1].

[1]. Minami H, et al. Functional analysis of norcoclaurine synthase in Coptis japonica. J Biol Chem. 2007;282(9):6274‐6282.

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