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VCP Activator 1

Katalog-Nr.GC71429

VCP Activator 1 ist ein VCP-Aktivator, der dosisabhängig die VCP-ATPase-Aktivität stimuliert.

Products are for research use only. Not for human use. We do not sell to patients.

VCP Activator 1 Chemische Struktur

Größe Preis Lagerbestand Menge
1 mg
180,00 $
Auf Lager
5 mg
468,00 $
Auf Lager
10 mg
756,00 $
Auf Lager

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Sample solution is provided at 25 µL, 10mM.

Description of VCP Activator 1

VCP Activator 1 is a VCP activator that dose-dependently stimulates VCP ATPase activity. VCP Activator 1 binds an allosteric pocket near the C-terminus. In addition, VCP Activator 1 binding site can also be occupied by a phenylalanine residue in the VCP C-terminal tail.

Chemical Properties of VCP Activator 1

Cas No. SDF
Formula C20H22N2O2S M.Wt 354.47
Löslichkeit DMSO : 300 mg/mL (846.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) Storage 4°C, sealed storage, away from moisture and light
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of VCP Activator 1

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.8211 mL 14.1056 mL 28.2111 mL
5 mM 0.5642 mL 2.8211 mL 5.6422 mL
10 mM 0.2821 mL 1.4106 mL 2.8211 mL
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Berechnen

In vivo Formulation Calculator (Clear solution) of VCP Activator 1

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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