Delafloxacin (Synonyms: ABT-492, RX-3341) |
| Catalog No.GC17324 |
A potent fluoroquinolone antibiotic
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 189279-58-1
Sample solution is provided at 25 µL, 10mM.
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Description:
IC50 Value: MICs ranging from 0.0078 to 0.125 micro g/ml for levofloxacin-resistant Streptococcus pneumoniae strains [1]
ABT-492 was more potent against quinolone-susceptible and -resistant gram-positive organisms, had activity similar to that of ciprofloxacin against certain members of the family Enterobacteriaceae, and had comparable activity against quinolone-susceptible, nonfermentative, gram-negative organisms.
in vitro: ABT-492 exhibited excellent in vitro activities against all 326 aerobic and anaerobic antral puncture sinus isolates tested with MICs (in micrograms per milliliter) at which 90% of the isolates tested were inhibited as follows: Haemophilus influenzae, 0.001; Moraxella catarrhalis, 0.008; and Streptococcus pneumoniae, 0.015 [2]. ABT-492 was as active as trovafloxacin against Chlamydia trachomatis, indicating good intracellular penetration and antibacterial activity [3].
in vivo: N/A
Clinical trial: N/A
Review for Delafloxacin
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for Delafloxacin
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