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DETA NONOate

Catalog No.GC18259

DETA NONOate Chemical Structure

A NO donor

Size Price Stock Qty
10mg
$45.00
In stock
50mg
$143.00
In stock
100mg
$265.00
In stock
500mg
$988.00
In stock

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Sample solution is provided at 25 µL, 10mM.

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Background

DETA NONOate is a NO donor. It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 20 hours and 56 hours at 37°C and 22-25°C, pH 7.4, respectively, to liberate 2 moles of NO per mole of parent compound.[1],[2]

Reference:

[1]. Hrabie, J.A., Klose, J.R., Wink, D.A., et al. New nitric oxide-releasing zwitterions derived from polyamines The Journal of Organic Chemistry 58, 1472-1476 (1993).
[2]. Keefer, L.K., Nims, R.W., Davies, K.M., et al. “NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms Methods in Enzymology 268, 281-293 (1996).

Chemical Properties

Cas No. 146724-94-9 SDF
Synonyms N/A
Chemical Name (Z)-1-[N-(2-aminoethyl)-N-(2-ammonioethyl)amino]diazen-1-ium-1,2-diolate
Canonical SMILES [NH3+]CCN(N(N=O)[O-])CCN
Formula C4H13N5O2 M.Wt 163.2
Solubility aqueous buffers: >100 mg/ml Storage Store at -80°C, protect from light
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

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Average Rating: 5 ★★★★★ (Based on Reviews and 32 reference(s) in Google Scholar.)

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