Dexrazoxane HCl (ICRF-187, ADR-529) |
Catalog No.GC11619 |
Topoisomerase II inhibitor,intracellular ion chelator,cardioprotective agent
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 149003-01-0
Sample solution is provided at 25 µL, 10mM.
Dexrazoxane hydrochloride (ICRF-187 hydrochloride) is a cardioprotective agent.
References:
[1]. Hasinoff BB. The use of dexrazoxane for the prevention of anthracycline extravasation injury. Expert Opin Investig Drugs. 2008 Feb;17(2):217-23.
[2]. Jones RL. Utility of dexrazoxane for the reduction of anthracycline-induced cardiotoxicity. Expert Rev Cardiovasc Ther. 2008 Nov;6(10):1311-7.
[3]. Lipshultz SE, Scully RE, Lipsitz SR et al. Assessment of dexrazoxane as a cardioprotectant in doxorubicin-treated children with high-risk acute lymphoblastic leukaemia: long-term follow-up of a prospective, randomised, multicentre trial. Lancet Oncol. 2010 Oct;11(10):950-61.
Average Rating: 5
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