DHODH-IN-5 |
| Catalog No.GC39374 |
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1644156-56-8
Sample solution is provided at 25 µL, 10mM.
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DHODH-IN-5 is a potent human dihydroorotate dehydrogenase (DHODH) inhibitor, with a pIC50 of 7.8 for human recombinant DHODH. DHODH-IN-5 inhibits measles virus replication, with a pMIC50 of 8.8[1].
[1]. Munier-Lehmann H, et al. Original 2-(3-alkoxy-1H-pyrazol-1-yl)pyrimidine derivatives as inhibitors of human dihydroorotate dehydrogenase (DHODH). J Med Chem. 2015 Jan 22;58(2):860-77.
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