Dimethindene maleate |
| Catalog No.GC66445 |
Dimethindene maleate is a selective histamine H1 antagonist with antihistamine effects. Dimethindene maleate can be used for the research of hypersensitivity reactions.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 3614-69-5
Sample solution is provided at 25 µL, 10mM.
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Dimethindene maleate is a selective histamine H1 antagonist with antihistamine effects. Dimethindene maleate can be used for the research of hypersensitivity reactions[1][2][3].
Dimethindene maleate (1-1000 μM) suppresses the cromakalim-induced/glibenclamide-sensitive K?? currents in a concentration-dependent and reversible manner with an IC50 value of 29.5 μM[2].
Dimethindene maleate (1-1000 μM) inhibits Y-26763-induced glibenclamide-sensitive K?? currents with an IC50 value of 49 μM[2].
Dimethindene maleate (0.25 mg; i.p. once) affects wound healing in mice[1].
| Animal Model: | C57BL/6 mice with wound healing[1] |
| Dosage: | 0.25 mg |
| Administration: | Intraperitoneal injection; 0.25 mg once |
| Result: | Significantly delayed skin wound and only showed wound closure impairment in the initial phase wound healing. |
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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