DL-Laudanosine |
| Catalog No.GC61864 |
DL-Laudanosine, an Atracurium and Cisatracurium metabolite, crosses the blood–brain barrier and may cause excitement and seizure activity.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1699-51-0
Sample solution is provided at 25 µL, 10mM.
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DL-Laudanosine, an Atracurium and Cisatracurium metabolite, crosses the blood-brain barrier and may cause excitement and seizure activity[1].
DL-Laudanosine (Laudanosine) appears to be unique in its ability to produce cerebral stimulation in lightly anaesthetized animals and it is reported to cause arousal from anaesthesia in subconvulsive doses[1].
References:
[1]. V Fodale, et al. Laudanosine, an Atracurium and Cisatracurium Metabolite. Eur J Anaesthesiol. 2002 Jul;19(7):466-73.
[2]. D J Chapple, et al. Cardiovascular and Neurological Effects of Laudanosine. Studies in Mice and Rats, and in Conscious and Anaesthetized Dogs. Br J Anaesth. 1987 Feb;59(2):218-25.
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