DMHAPC-Chol (Synonyms: Dimethyl Hydroxyethyl Aminopropane Carbamoyl Cholesterol Iodide) |
| Catalog No.GC43503 |
DMHAPC-Chol is a cationic cholesterol.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 794494-38-5
Sample solution is provided at 25 µL, 10mM.
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DMHAPC-Chol is a cationic cholesterol. Liposomes containing DMHAPC-chol have been used for DNA plasmid delivery in vitro and in vivo in a B16-F10 mouse xenograft model. Liposomes containing DMHAPC-chol are cytotoxic to B16-F10 cells when used at lipid concentrations greater than 20 µM. DMHAPC-Chol, as part of a lipoplex with DOPE , has also been used to deliver DNA into mouse lung via intratracheal injection, resulting in a heterogeneous distribution in the bronchi and bronchioles, and to deliver VEGF siRNA into A431 and MDA-MB-231 cells, which secrete VEGF.
Average Rating: 5 (Based on Reviews and 37 reference(s) in Google Scholar.)
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