Dopexamine hydrochloride (FPL60278AR) |
| Catalog No.GC32627 |
Dopexamine hydrochloride (FPL60278AR) is a β2 adrenergic receptor agonist.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 86484-91-5
Sample solution is provided at 25 µL, 10mM.
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Dopexamine hydrochloride is a β2 adrenergic receptor agonist.
Dopexamine is a dopamine analogue with agonist activity at β2 and dopaminergic receptors. Dopexamine can attenuate the systemic inflammatory response, reduce tissue leukocyte infiltration, and protect against organ injury at doses that do not alter global hemodynamics or regional microvascular flow[1]. Dopexamine is a dopamine analog that stimulates β-adrenergic and dopamine 1 and 2 receptors, conferring some vasodilatory effects. Dopexamine reduces the systemic inflammatory response to endotoxin, including cytokine release, endothelial adhesion molecules, and oxidative stress, without substantially changing systemic hemodynamics, either blood pressure or stroke volume[2].
[1]. Bangash MN, et al. Dopexamine can attenuate the inflammatory response and protect against organ injury in the absence of significant effects on hemodynamics or regional microvascular flow. Crit Care. 2013 Mar 28;17(2):R57. [2]. Hollenberg SM. Dopexamine: immunomodulatory, hemodynamic, or both? Crit Care. 2013 May 13;17(3):143.
Average Rating: 5 (Based on Reviews and 17 reference(s) in Google Scholar.)
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