DSPE-PEG(2000)-NHS |
| Catalog No.GC52333 |
A PEGylated derivative of DSPE
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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DSPE-PEG(2000)-NHS is a PEGylated derivative of 1,2-distearoyl-sn-glycero-3-PE .1 It has been used in the generation of micelles and in combination with other lipids in the formation of liposomes. DSPE-PEG(2000)-NHS-containing liposomes localize to the liver and tumor after intravenous administration in mice. Liposomes containing DSPE-PEG(2000)-NHS conjugated to the breast cancer targeting H6 peptide and encapsulating the DNA topoisomerase inhibitor doxorubicin reduce tumor growth in an SK-BR-3 breast cancer mouse xenograft model.
1.Jia, X., Wang, W., Han, Q., et al.Micromixer based preparation of functionalized liposomes and targeting drug deliveryACS Med. Chem. Lett.7(4)429-434(2016)
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