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DUBs-IN-3 Catalog No.GC10356

potent deubiquitinase enzyme inhibitor

Size Price Stock Qty
10 mM * 1 mL in DMSO
$318.00
In stock
2mg
$201.00
In stock
5mg
$302.00
In stock
10mg
$432.00
In stock
50mg
$1,294.00
In stock
100mg
$1,811.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Quality Control

Quality Control & SDS

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Chemical Properties

Cas No. 924296-17-3 SDF
Synonyms N/A
Chemical Name (E)-9-((allyloxy)imino)-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile
Canonical SMILES C=CCO/N=C1C2=CC=CC=C2C3=C\1N=C(C(C#N)=N3)C#N
Formula C16H9N5O M.Wt 287.28
Solubility Soluble in DMSO Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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Background

DUBs-IN-3 is a potent deubiquitinase (USP) enzyme inhibitor extracted from reference compound 22c with an IC50 of 0.56 μM for USP8.

References:
[1]. Colombo M, et al. Synthesis and biological evaluation of 9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile analogues as potential inhibitors of deubiquitinating enzymes. ChemMedChem. 2010 Apr 6;5(4):552-8.