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Dynamin inhibitory peptide, myristoylated

Catalog No.GC50020

Cell-permeable dynamin inhibitor

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Dynamin inhibitory peptide, myristoylated Chemical Structure

Cas No.: 251634-22-7

Size Price Stock Qty
1 mg
$384.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Cell-permeable version of dynamin inhibitory peptide, an inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. Reduces NMDA receptor internalization. Control Peptide also available.

Grabs et al (1997) The SH3 domain of amphiphysin binds the proline-rich domain of dynamin at a single site that defines a new SH3 binding consensus sequence. J.Biol.Chem. 272 13419 PMID:9148966 |Kittler et al (2000) Constitutive endocytosis of GABAA receptors by an association with the adaptin AP2 complex modulates inhibitory synaptic currents in hippocampal neurons. J.Neurosci. 20 7972 PMID:11050117 |Nong et al (2003) Glycine binding primes NMDA receptor internalization. Nature 422 302 PMID:12646920

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