E3 Ligase Ligand-Linker Conjugates 21 (Synonyms: Cereblon Ligand-Linker Conjugates 3 ; E3 Ligase Ligand-Linker Conjugates 14) |
Catalog No.GC33103 |
E3 Ligase Ligand-Linker Conjugates 21 (Cereblon Ligand-Linker Conjugates 3) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
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Cas No.: 1957236-20-2
Sample solution is provided at 25 µL, 10mM.
E3 Ligase Ligand-Linker Conjugates 21 is a synthesized compound that incorporates an E3 ligase ligand and a linker used in PROTAC technology.
E3 Ligase Ligand-Linker Conjugates 21 is composed of Degron (E3 ubiquitin ligase) and a linker, and they are used in PROTAC technology. E3 Ligase Ligand-Linker Conjugates 21 binds to the targeting ligand to induce the target protein (including BRD4, BRD2, and BRD3) degradation[1].
[1]. Methods to induce targeted protein degradation through bifunctional molecules. WO 2017007612 A1
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