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Eledoisin (Eledone peptide) (Synonyms: ELD 950, Moschatin)

Catalog No.GC30285

A neurokinin receptor agonist

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Eledoisin (Eledone peptide) Chemical Structure

Cas No.: 69-25-0

Size Price Stock Qty
1mg
$46.00
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5mg
$65.00
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10mM (in 1mL Water)
$83.00
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50mg
$111.00
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100mg
$130.00
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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

Eledoisin is a specific agonist of NK2 and NK3 receptors.

Eledoisin increases the value recorded under basal conditions by 24.5±3.7%; this stimulation is significantly (P<0.01) lowered to 13.1±1.9% by the simultaneous presence of CP99994. The same protocol is also used to characterize the sensitivity of Eledoisin stimulation to 0.1 μM SR48968 or 0.1 μM SB222200. SR48968 significantly (P < 0.01) lower the stimulation by Eledoisin, while SB222200 has no effect. Eledoisin stimulation is reduced by CP99994 and SR48968, NK1 and NK2 antagonists, respectively[1].

Eledoisin (0.1-1 nmol/kg) injected into rats produces a biphasic cardiovascular response that consists of an initial fall of systemic blood pressure (8-15 mm Hg) followed by a rise (20-22 mm Hg). Intracerebroventricular injection of Eledoisin produces an enhancement of grooming and scratching behavior in mice[2].

[1]. Lippe C, et al. Eledoisin and Kassinin, but not Enterokassinin, stimulate ion transport in frog skin. Peptides. 2004 Nov;25(11):1971-5. [2]. Severini C, et al. The tachykinin peptide family. Pharmacol Rev. 2002 Jun;54(2):285-322.

Chemical Properties

Cas No. 69-25-0 SDF
Synonyms ELD 950, Moschatin
Canonical SMILES {Glp}-Pro-Ser-Lys-Asp-Ala-Phe-Ile-Gly-Leu-Met-NH2
Formula C54H85N13O15S M.Wt 1188.4
Solubility Water : 18.15 mg/mL (15.27 mM) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 0.8415 mL 4.2073 mL 8.4147 mL
5 mM 0.1683 mL 0.8415 mL 1.6829 mL
10 mM 0.0841 mL 0.4207 mL 0.8415 mL
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Average Rating: 5 ★★★★★ (Based on Reviews and 38 reference(s) in Google Scholar.)

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