Enpp-1-IN-14 |
| Catalog No.GC66042 |
ENPP1-IN-2 is a potent Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) inhibitor with an IC50 value of 32.38 nM for recombinant human ENPP-1. ENPP1-IN-2 has anti-tumor activity.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2687222-59-7
Sample solution is provided at 25 µL, 10mM.
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ENPP1-IN-2 is a potent Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) inhibitor with an IC50 value of 32.38 nM for recombinant human ENPP-1. ENPP1-IN-2 has anti-tumor activity[1].
ENPP1-IN-2 (compound 015) (50 mg/kg; IP; BID, for 31 days) significantly inhibits tumor growth[1].
| Animal Model: | Female C57BL/6 mice (4-6 weeks; implanted subcutaneously with 2×105 MC38 cells)[1] |
| Dosage: | 50 mg/kg |
| Administration: | IP; BID, for 31 days (given a single 10 Gy exposure of focal radiation to the tumor site) |
| Result: | Significantly inhibited tumor growth. |
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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