ERB-196 (WAY-202196) (Synonyms: WAY-202196) |
| Catalog No.GC30650 |
ERB-196 (WAY-202196) is a nonsteroidal selective estrogen receptor-β (ERβ) agonist.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 550997-55-2
Sample solution is provided at 25 µL, 10mM.
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ERB-196 is a nonsteroidal selective estrogen receptor-β (ERβ) agonist.
ERB-196 is a nonsteroidal selective estrogen receptor-β (ERβ) agonist. ERB-196 significantly reduces histopathologic evidence of injury to the gastrointestinal mucosal surface (0.7±0.1 vs. 2.3±0.2 for control; p<0.05). The mucosal mass of 10-cm segments of small bowel mucosa shows better preservation of mucosal mass than control treatment (63±20 [ERB-196] vs. 31±24 [control]), but this difference fails to reach statistical significance (p<0.06). The administration of ERB-196 is highly effective in the prevention of lethality. Consistent with the neutropenic rat model, ERB-196 significantly increases survival when compare with vehicle control[1].
[1]. Cristofaro PA, et al. WAY-202196, a selective estrogen receptor-beta agonist, protects against death in experimental septic shock. Crit Care Med. 2006 Aug;34(8):2188-93.
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