Ethyl p-methoxycinnamate (Synonyms: EPMC, Ethyl 4-methoxycinnamate, Ethyl para-methoxycinnamate) |
| Catalog No.GC43635 |
Ethyl p-methoxycinnamate is a natural product found in Kaempferia galangal with anti-inflammatory, anti-neoplastic and anti-microbial effects.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 24393-56-4
Sample solution is provided at 25 µL, 10mM.
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Ethyl p-methoxycinnamate (EPMC) is a natural product found in K. galanga and C. zedoaria extracts with anti-inflammatory, antiangiogenic, antifungal, larvicidal, and analgesic activities. It inhibits COX-1 and COX-2 in vitro (IC50s = 1.12 and 0.83 μM, respectively) and reduces IL-1 and TNF-α production in vivo. EPMC inhibits granuloma tissue formation and acts as an analgesic, delaying tail flick time, in a dose-dependent manner in rats. It inhibits blood vessel growth in rat aortic explants (IC50 = 91.9 μg/ml). EPMC (T. rubrum, A. niger, S. cerevisiae, and E. floccosum and is larvicidal (LC50 = 53.64 ppm) against Ae. aegypti.
Average Rating: 5 (Based on Reviews and 31 reference(s) in Google Scholar.)
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