Fabomotizole hydrochloride (CM346 hydrochloride) (Synonyms: SM-346) |
| Catalog No.GC30903 |
Fabomotizole hydrochloride (CM346 hydrochloride) (CM346 hydrochloride) is an anxiolytic drug.
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Cas No.: 173352-39-1
Sample solution is provided at 25 µL, 10mM.
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Fabomotizole Hcl (CM346 Hcl) is an anxiolytic drug; produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions.IC50 value:Target: anxiolytic agent Afobazole's mechanism of action remains poorly defined however, with GABAergic, NGF and BDNF release promoting, MT1 receptor antagonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Afobazole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Afobazole has found little clinical use outside of Russia and has not been evaluated by the FDA.
[1]. Afobazole, From Wikipedia
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