FKBP52 Monoclonal Antibody (Clone Hi52C) |
Catalog No.GC49695 |
For immunochemical analysis of FKBP52
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: N/A
Sample solution is provided at 25 µL, 10mM.
Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Hsp90 is crucial to cellular signaling by its regulation of the folding, activity, and stability of a wide range of client proteins. These client protein complexes may also contain one or more co-
1.Cheung-Flynn, J., Roberts, P.J., Riggs, D.L., et al.C-terminal sequences outside the tetratricopeptide repeat domain of FKBP51 and FKBP52 cause differential binding to Hsp90The Journal of Biological Chemisty278(19)17388-17394(2003) 2.Davies, T.H., Ning, Y.M., and SÁnchez, E.R.A new first step in activation of steroid receptors. Hormone-induced switching of FKBP51 and FKBP52 immunophilinsThe Journal of Biological Chemisty277(7)4597-4600(2002) 3.Wu, B., Li, P., Liu, Y., et al.3D structure of human FK506-binding protein 52: Implications for the assembly of the glucocorticoid receptor/Hsp90/immunophilin hetrocomplexThe Journal of Biological Chemisty101(22)8348-8353(2004) 4.Denny, W.B., Prapapanich, V., Smith, D.F., et al.Structure-function analysis of squirrel monkey FK506-binding protein 51, a potent inhibitor of glucocorticoid receptor activityEndocrinology146(7)3194-3201(2005) 5.Cox, M.B., Riggs, D.L., Hessling, M., et al.FK506-binding protein 52 phosphorylation: A potential mechanism for regulating steroid hormone receptor activityMol. Endocrinol.21(12)2956-2967(2007)
Cas No. | N/A | SDF | Download SDF |
Canonical SMILES | N/A | ||
Formula | N/A | M.Wt | 52 |
Solubility | N/A | Storage | -20°C |
General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. |
Prepare stock solution | |||
1 mg | 5 mg | 10 mg | |
1 mM | 19.2308 mL | 96.1538 mL | 192.3077 mL |
5 mM | 3.8462 mL | 19.2308 mL | 38.4615 mL |
10 mM | 1.9231 mL | 9.6154 mL | 19.2308 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Average Rating: 5
(Based on Reviews and 25 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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