Fluocortolone (Synonyms: SH 742) |
| Catalog No.GC49631 |
A glucocorticoid
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 152-97-6
Sample solution is provided at 25 µL, 10mM.
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Fluocortolone is a glucocorticoid.1,2 It inhibits progesterone 3α-hydroxysteroid dehydrogenase in rat cortical homogenates (IC50 = 40 µM).1 Fluocortolone (3, 6, and 12 mg/kg) decreases adjuvant-induced paw edema in rats.2
1.StÜrenburg, H.J., Fries, U., and Kunze, K.Glucocorticoids and anabolic/androgenic steroids inhibit the synthesis of GABAergic steroids in rat cortexNeuropsychobiology35(3)143-146(1997) 2.Bhargava, A.S.Effect of anti-inflammatory agents on adjuvant-induced edema modified for primary testPharmacol. Res. Commun.3(1)83-91(1971)
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