(±)-SDZ-201 106 (Synonyms: DPI 201-106) |
| Catalog No.GC41677 |
(±)-SDZ-201 106 (SDZ 201106) est un agent cardiotonique avec un mécanisme d'action synergique sarcolemmique et intracellulaire.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 97730-95-5
Sample solution is provided at 25 µL, 10mM.
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(±)-SDZ-201 106 is a diphenylpiperazinylindole derivative that prolongs the open state of cardiac voltage-gated Na+ channels. It has been shown to increase net Na+ influx and the activity of reverse mode Na+/Ca2+ exchange, which leads to an increase in intracellular Ca2+, as well as to partially inhibit the Na+ pump in cardiac myocytes. (±)-SDZ-201 106 is also reported to act as an open-channel blocker of delayed-rectifier K+ channels in NG108-15 neuronal cells.
Average Rating: 5 (Based on Reviews and 3 reference(s) in Google Scholar.)
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