Accueil>>20-hydroxy N-Arachidonoyl Taurine

20-hydroxy N-Arachidonoyl Taurine

Catalog No.GC42085

Arachidonic acid is metabolized by cytochrome P450 (CYP450) 4A ω-hydroxylase to 20-HETE, which acts as a vasoconstrictor in the kidney and brain.

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20-hydroxy N-Arachidonoyl Taurine Chemical Structure

Taille Prix Stock Qté
25μg
204,00 $US
En stock
50μg
387,00 $US
En stock
100μg
733,00 $US
En stock
500μg Please Inquire Please Inquire

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

Arachidonic acid is metabolized by cytochrome P450 (CYP450) 4A ω-hydroxylase to 20-HETE, which acts as a vasoconstrictor in the kidney and brain. During mass spectrometry lipidomics analysis of rat brain, a series of fatty acyl amides of taurine was discovered, of which arachidonoyl taurine is a prominent member. 20-hydroxy N-Arachidonoyl taurine is a potential CYP450 metabolite of N-arachidonoyl taurine and may activate members of the transient receptor potential (TRP) family of calcium channels.

Chemical Properties

Cas No. SDF
Canonical SMILES OCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCS(=O)(=O)O
Formula C22H37NO5S M.Wt 427.6
Solubility DMF: 10 mg/ml,DMSO: 20 mg/ml,Ethanol: 1 mg/ml,PBS (pH 7.2): 0.5 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 2.3386 mL 11.6932 mL 23.3863 mL
5 mM 0.4677 mL 2.3386 mL 4.6773 mL
10 mM 0.2339 mL 1.1693 mL 2.3386 mL
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Review for 20-hydroxy N-Arachidonoyl Taurine

Average Rating: 5 ★★★★★ (Based on Reviews and 25 reference(s) in Google Scholar.)

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