Accueil>>Signaling Pathways>> Ox Stress Reagents>> Lipid Peroxidation>>4-hydroxy Nonenal Alkyne

4-hydroxy Nonenal Alkyne (Synonyms: Click Tag 4HNE Alkyne)

Catalog No.GC42411

4-hydroxy Nonenal (4-HNE) is a major aldehyde produced during the lipid peroxidation of ω-6 polyunsaturated fatty acids, such as arachidonic acid and linoleic acid.

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4-hydroxy Nonenal Alkyne Chemical Structure

Cas No.: 1011268-23-7

Taille Prix Stock Qté
100μg
74,00 $US
En stock
500μg
332,00 $US
En stock
1mg
589,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

4-hydroxy Nonenal (4-HNE) is a major aldehyde produced during the lipid peroxidation of ω-6 polyunsaturated fatty acids, such as arachidonic acid and linoleic acid. It is considered a potential causal agent in numerous diseases, including chronic inflammation, neurodegenerative diseases, atherosclerosis, diabetes, and cancer, in part because it covalently modifies DNA and proteins resulting in genetic mutations and altered cell signaling, respectively. 4-HNE Alkyne is a form of 4-HNE with a terminal alkyne. Such terminal alkyne groups can be used in linking reactions, known as click chemistry, characterized by high dependability and specificity of azide-alkyne bioconjugation reactions. Click chemistry has only recently been applied to the study of oxidized lipids.

Chemical Properties

Cas No. 1011268-23-7 SDF
Synonymes Click Tag 4HNE Alkyne
Canonical SMILES [H]C(/C=C/C(O)CCCC#C)=O
Formula C9H12O2 M.Wt 152.2
Solubility DMF: 2.5 mg/ml,DMSO: 2 mg/ml,Ethanol: 12.5 mg/ml,PBS (pH 7.2): 5 mg/ml Storage Store at -80°C; protect from light
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 6.5703 mL 32.8515 mL 65.703 mL
5 mM 1.3141 mL 6.5703 mL 13.1406 mL
10 mM 0.657 mL 3.2852 mL 6.5703 mL
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Average Rating: 5 ★★★★★ (Based on Reviews and 14 reference(s) in Google Scholar.)

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