Accueil>>Lipids>> Fatty Acids>>4-oxo Docosahexaenoic Acid

4-oxo Docosahexaenoic Acid (Synonyms: 4-oxo DHA)

Catalog No.GC41530

4-oxo Docosahexaenoic acid (4-oxo DHA) is a putative metabolite of DHA with antiproliferative and PPARγ agonist activity.

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4-oxo Docosahexaenoic Acid Chemical Structure

Cas No.: 845673-74-7

Taille Prix Stock Qté
25μg
67,00 $US
En stock
50μg
127,00 $US
En stock
100μg
240,00 $US
En stock
250μg
535,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

4-oxo Docosahexaenoic acid (4-oxo DHA) is a putative metabolite of DHA with antiproliferative and PPARγ agonist activity. It inhibits the growth of several triple negative breast cancer cell lines (MCF-10F, trMCF, bsMCF, MDA-MB-231, and BT549) at 50-100 µM, however it increased proliferation of MCF-7 cells. 4-oxo DHA binds covalently to PPARγ and activates gene transcription in luciferase reporter assays and in dendritic cells with EC50 values of approximately 8-16 µM.

Chemical Properties

Cas No. 845673-74-7 SDF
Synonymes 4-oxo DHA
Canonical SMILES CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C=C\C(CCC(O)=O)=O
Formula C22H30O3 M.Wt 342.5
Solubility DMF: 50 mg/ml,DMSO: 50 mg/ml,Ethanol: 50 mg/ml,PBS (pH 7.2): 0.1 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 2.9197 mL 14.5985 mL 29.1971 mL
5 mM 0.5839 mL 2.9197 mL 5.8394 mL
10 mM 0.292 mL 1.4599 mL 2.9197 mL
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Review for 4-oxo Docosahexaenoic Acid

Average Rating: 5 ★★★★★ (Based on Reviews and 13 reference(s) in Google Scholar.)

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