7-Chloro-4-(piperazin-1-yl)quinoline |
| Catalog No.GC62651 |
La 7-chloro-4-(pipérazin-1-yl)quinolone est un échafaudage important en chimie médicinale.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 837-52-5
Sample solution is provided at 25 µL, 10mM.
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7-Chloro-4-(piperazin-1-yl)quinolone is an important scaffold in medicinal chemistry. 7-Chloro-4-(piperazin-1-yl)quinolone is a potent sirtuin inhibitor and also inhibits the serotonin uptake (IC50 of 50 μM). 7-Chloro-4-(piperazin-1-yl)quinolone exhibits antimalarial activity on D10 and K1 strains of P. falciparum with IC50s of 1.18 μM and 0.97 μM, respectively[1].
[1]. Aida M Abd El-Sattar El-Azzouny, et al. Structural and biological survey of 7-chloro-4-(piperazin-1-yl)quinoline and its derivatives. Drug Dev Res. 2020 Nov;81(7):786-802.
Average Rating: 5 (Based on Reviews and 15 reference(s) in Google Scholar.)
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