Accueil>>Signaling Pathways>> Neuroscience>> Behavioral Neuroscience>>α-Cortolone

α-Cortolone (Synonyms: 20α-Cortolone, NSC 59872)

Catalog No.GC49838

A metabolite of cortisol

Products are for research use only. Not for human use. We do not sell to patients.

α-Cortolone Chemical Structure

Cas No.: 516-42-7

Taille Prix Stock Qté
1 mg
126,00 $US
En stock
5 mg
564,00 $US
En stock
10 mg
940,00 $US
En stock
25 mg
1 568,00 $US
En stock

Tel:(909) 407-4943 Email: sales@glpbio.com


Avis des clients

Based on customer reviews.

  • GlpBio Citations

    GlpBio Citations
  • Bioactive Compounds Premium Provider

    Bioactive Compounds Premium Provider

Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

α-Cortolone is a metabolite of the glucocorticoid cortisol .1 It is formed from cortisol by 20α-hydroxysteroid dehydrogenase (20α-HSD) via a tetrahydrocortisone intermediate. Urinary levels of α-cortolone are decreased in patients with severe anorexia nervosa and in postmenopausal women with endometrial adenocarcinoma compared to postmenopausal women without endometrial adenocarcinoma.2,3

1.Espiard, S., McQueen, J., Sherlock, M., et al.Improved urinary cortisol metabolome in Addison disease: A prospective trial of dual-release hydrocortisoneJ. Clin. Endocrinol. Metab.106(3)814-825(2021) 2.Wassif, W.S., McLoughlin, D.M., Vincent, R.P., et al.Steroid metabolism and excretion in severe anorexia nervosa: Effects of refeedingAm. J. Clin. Nutr.93(5)911-917(2011) 3.Bufa, A., BÍrÓ, I., PoÓr, V., et al.Altered urinary profiles of endogenous steroids in postmenopausal women with adenocarcinoma endometriiGynecol. Endocrinol.26(1)10-15(2010)

Avis

Review for α-Cortolone

Average Rating: 5 ★★★★★ (Based on Reviews and 13 reference(s) in Google Scholar.)

5 Star
100%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%
Review for α-Cortolone

GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.

Required fields are marked with *

You may receive emails regarding this submission. Any emails will include the ability to opt-out of future communications.